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Published in 2019 at "Molecular psychiatry"
DOI: 10.1038/s41380-019-0589-8
Abstract: Dysfunction in a wide array of systems—including the immune, monoaminergic, and glutamatergic systems—is implicated in the pathophysiology of depression. One potential intersection point for these three systems is the kynurenine (KYN) pathway. This study explored…
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Keywords:
post ketamine;
monoaminergic glutamatergic;
glutamatergic systems;
kyn pathway ... See more keywords
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Published in 2022 at "Biomarkers"
DOI: 10.1080/1354750x.2022.2049367
Abstract: Abstract Introduction Drug addiction is associated with disruption of a multitude of biomarkers in various brain regions, particularly in the reward centre. The most pronounced are dopaminergic and glutamatergic biomarkers, which are affected at various…
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Keywords:
glutamatergic systems;
glutamatergic biomarkers;
drug addiction;
dopaminergic glutamatergic ... See more keywords
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Published in 2020 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a039602
Abstract: Glutamate is the main excitatory neurotransmitter in the brain and is of critical importance for the synaptic and circuit mechanisms that underlie opioid addiction. Opioid memories formed over the course of repeated drug use and…
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Keywords:
addiction;
systems memory;
glutamatergic systems;
opioid addiction ... See more keywords