Metabotropic glutamate and GABA receptors modulate cellular excitability and glutamatergic transmission in chicken cochlear nucleus angularis neurons
Sign Up to like & getrecommendations! Published in 2017 at "Hearing Research"
DOI: 10.1016/j.heares.2017.01.011
Abstract: Abstract Neurons in the avian cochlear nucleus angularis (NA) receive glutamatergic input from the auditory nerve, and GABAergic input from the superior olivary nucleus. Physiologically heterogeneous, NA neurons perform multiple functions including encoding sound intensity… read more here.
Keywords: cochlear nucleus; group; nucleus angularis; glutamatergic transmission ... See more keywords
Riluzole attenuates the efficacy of glutamatergic transmission by interfering with the size of the readily releasable neurotransmitter pool
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.09.021
Abstract: ABSTRACT Riluzole is a potent neuroprotective agent which primarily inhibits excitatory neurotransmission interfering with presynaptic release, uptake and postsynaptic actions of glutamate by mechanisms that are not well understood. Riluzole and related prodrugs with improved… read more here.
Keywords: efficacy glutamatergic; readily releasable; size readily; glutamatergic transmission ... See more keywords
Alcohol intake enhances glutamatergic transmission from D2 receptor-expressing afferents onto D1 receptor-expressing medium spiny neurons in the dorsomedial striatum
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-019-0332-9
Abstract: Dopaminergic modulation of corticostriatal transmission is critically involved in reward-driven behaviors. This modulation is mainly mediated by dopamine D1 receptors (D1Rs) and D2Rs, which are highly expressed in medium spiny neurons (MSNs) of the dorsomedial… read more here.
Keywords: transmission; glutamatergic transmission; receptor; expressing afferents ... See more keywords
Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn7357
Abstract: Schizophrenia is a polygenetic disease, the heterogeneity of which is likely complicated by epigenetic modifications yet to be elucidated. Here, we performed transcriptomic analysis of peripheral blood RNA from monozygotic twins discordant for schizophrenia and… read more here.
Keywords: glutamatergic transmission; loss; sociability memory; mir 501 ... See more keywords
Recovery of Chronic Stress-Triggered Changes of Hippocampal Glutamatergic Transmission
Sign Up to like & getrecommendations! Published in 2018 at "Neural Plasticity"
DOI: 10.1155/2018/9360203
Abstract: Chronic stress results in neurochemical, physiological, immune, molecular, cellular, and structural changes in the brain and often dampens the cognition. The hippocampus has been one major focus in studying the stress responsivity and neural mechanisms… read more here.
Keywords: glutamatergic transmission; chronic stress; stress; recovery chronic ... See more keywords
Perturbation of Ephrin Receptor Signaling and Glutamatergic Transmission in the Hypothalamus in Depression Using Proteomics Integrated With Metabolomics
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.01359
Abstract: Hypothalamic dysfunction is a key pathological factor in inflammation-associated depression. In the present study, isobaric tags for relative-absolute quantitation (iTRAQ) combined with mass spectrometry and gas chromatography-mass spectrometry (GC-MS) were employed to detect the proteomes… read more here.
Keywords: depression; ephrin receptor; glutamatergic transmission; receptor signaling ... See more keywords