Cysteine synthase A overexpression in Corynebacterium glutamicum enhances l‐isoleucine production
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1698
Abstract: Cysteine synthase A (CysK) catalyzes the last reaction of l‐cysteine synthesis in bacteria, but its moonlighting functions have been revealed recently. In this study, CysK was overexpressed in Corynebacterium glutamicum IWJ001, an l‐isoleucine producer. Compared… read more here.
Keywords: iwj001 pdxw; pdxw; glutamicum; cysk ... See more keywords
Chromosomal editing of Corynebacterium glutamicum ATCC 13032 to produce gamma‐aminobutyric acid
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2324
Abstract: Corynebacterium glutamicum has been used as a sustainable microbial producer for various bioproducts using cheap biomass resources. In this study, a high GABA‐producing C. glutamicum strain was constructed by chromosomal editing. Lactobacillus brevis‐derived gadB2 was… read more here.
Keywords: corynebacterium glutamicum; atcc 13032; chromosomal editing; glutamicum atcc ... See more keywords
Improvement of acetyl-CoA supply and glucose utilization increases l-leucine production in Corynebacterium glutamicum.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology journal"
DOI: 10.1002/biot.202100349
Abstract: BACKGROUND l-Leucine is one of important essential amino acids with multiple industrial applications, whose market requirements cannot be met because of the lower productivity. MAIN METHODS AND MAJOR RESULTS In this study, a strain of… read more here.
Keywords: acetyl; coa supply; acetyl coa; glutamicum ... See more keywords
CRISPR interference-mediated metabolic engineering of Corynebacterium glutamicum for homo-butyrate production.
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.26720
Abstract: Combinatorial metabolic engineering enabled the development of efficient microbial cell factories for modulating gene expression to produce desired products. Here, we report the combinatorial metabolic engineering of Corynebacterium glutamicum to produce butyrate by introducing a… read more here.
Keywords: production; butyrate; metabolic engineering; glutamicum ... See more keywords
Engineering Corynebacterium glutamicum for synthesis of poly(3‐hydroxybutyrate) from lignocellulose biomass
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28065
Abstract: Lignocellulose is the only feasible carbohydrates feedstock for commercial scale and carbon neutral production of poly(3‐hydroxybutyrate) (PHB) biopolymer by its great abundance and availability. Microbial cell factories for fermentative PHB synthesis are highly restricted by… read more here.
Keywords: cell; phb; synthesis; glutamicum ... See more keywords
Study of the effect of culture mediums on the amino acid metabolites for Corynebacterium glutamicum using high‐speed micellar electrokinetic chromatography
Sign Up to like & getrecommendations! Published in 2019 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201900010
Abstract: Corynebacterium glutamicum (C. glutamicum) is a well‐known workhorse for the industrial production of amino acids. Different carbon, nitrogen, and sulfur source may force the bacterium to produce specific metabolites. In this work, a method of… read more here.
Keywords: amino acid; glutamicum; culture mediums; corynebacterium glutamicum ... See more keywords
Analysis of Novel Antioxidant Sesquarterpenes (C35 Terpenes) Produced in Recombinant Corynebacterium glutamicum
Sign Up to like & getrecommendations! Published in 2018 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-018-2756-9
Abstract: Novel synthetic isoprenoids have been synthesized in engineered microbial hosts by evolving terpene synthase or expressing heterologous terpene synthases. Recently, the native operon, crtNaNcM derived from Planococcus sp. PAMC 21323, has isolated for potential industrial… read more here.
Keywords: pces h36; analysis novel; glutamicum; c35 ... See more keywords
Enhancement of anaerobic lysine production in Corynebacterium glutamicum electrofermentations.
Sign Up to like & getrecommendations! Published in 2017 at "Bioelectrochemistry"
DOI: 10.1016/j.bioelechem.2017.06.001
Abstract: It has been suggested that application of electric potential can affect lysine producing fermentations, although experimental evidence is lacking. To study this hypothesis we used the lysine producer Corynebacterium glutamicum ZW04, and we exposed it… read more here.
Keywords: corynebacterium glutamicum; glutamicum; lysine; lysine production ... See more keywords
Miniaturized and automated adaptive laboratory evolution: Evolving Corynebacterium glutamicum towards an improved d-xylose utilization.
Sign Up to like & getrecommendations! Published in 2017 at "Bioresource technology"
DOI: 10.1016/j.biortech.2017.05.055
Abstract: Adaptive Laboratory Evolution (ALE) is increasingly being used as a technique for untargeted strain optimization. This work aimed at developing an automated and miniaturized ALE approach based on repetitive batch cultivations in microtiter plates. The… read more here.
Keywords: laboratory evolution; towards improved; glutamicum; corynebacterium glutamicum ... See more keywords
Xylose as preferred substrate for sarcosine production by recombinant Corynebacterium glutamicum.
Sign Up to like & getrecommendations! Published in 2019 at "Bioresource technology"
DOI: 10.1016/j.biortech.2019.02.084
Abstract: The aim of this work was to study the fermentative production of the N-methylated amino acid sarcosine by C. glutamicum. Characterization of the imine reductase DpkA from Pseudomonas putida revealed that it catalyses N-methylamination of… read more here.
Keywords: production; glutamicum; sarcosine; glucose based ... See more keywords
Mechanosensitive channels of Corynebacterium glutamicum functioning as exporters of l-glutamate and other valuable metabolites.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2020.05.005
Abstract: In the industrial l-glutamate production established on the use of Corynebacterium glutamicum, l-glutamate synthesized intracellularly is exported through mechanosensitive transmembrane channel proteins (MscCG and MscCG2) activated by the force-from-lipids. The involvement of MscCG2 in l-glutamate… read more here.
Keywords: channels corynebacterium; glutamicum; corynebacterium glutamicum; glutamate ... See more keywords