Maternal glutamine supplementation in murine succinic semialdehyde dehydrogenase deficiency, a disorder of γ‐aminobutyric acid metabolism
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12107
Abstract: Murine succinic semialdehyde dehydrogenase deficiency (SSADHD) manifests with high concentrations of γ‐aminobutyric acid (GABA) and γ‐hydroxybutyrate (GHB) and low glutamine in the brain. To understand the pathogenic contribution of central glutamine deficiency, we exposed aldh5a1−/−… read more here.
Keywords: glutamine supplementation; deficiency; gaba; brain ... See more keywords
Acute glutamine supplementation does not improve 20-km self-paced cycling performance in the heat
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Applied Physiology"
DOI: 10.1007/s00421-019-04234-2
Abstract: The premise of this study was to investigate the effect of acute glutamine supplementation on 20 km time trial cycling performance in the heat, neuromuscular function, inflammation and endotoxemia. Twelve cyclists completed two, 20-km time… read more here.
Keywords: heat; glutamine supplementation; glutamine; performance heat ... See more keywords
The Efficacy of Glutamine Supplementation in Severe Adult Burn Patients: A Systematic Review With Trial Sequential Meta-Analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Critical care medicine"
DOI: 10.1097/ccm.0000000000005887
Abstract: OBJECTIVES Evidence supporting glutamine supplementation in severe adult burn patients has created a state of uncertainty due to the variability in the treatment effect reported across small and large randomized controlled trials (RCTs). We aimed… read more here.
Keywords: supplementation; glutamine supplementation; severe adult; burn patients ... See more keywords
Glutamine is essential for overcoming the immunosuppressive microenvironment in malignant salivary gland tumors
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.1101/2022.04.29.490103
Abstract: Rationale Immunosuppression in the tumor microenvironment (TME) is key to the pathogenesis of solid tumors. Tumor cell-intrinsic autophagy is critical for sustaining both tumor cell metabolism and survival. However, the role of autophagy in the… read more here.
Keywords: gland tumors; glutamine supplementation; dietary glutamine; tumor ... See more keywords
Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0008125
Abstract: Background The disturbance of host metabolic pathways by Leishmania parasites has crucial consequences for the activation status of immune cells and the outcome of infection. Glutamine has been described as an immunomodulatory amino acid, yet… read more here.
Keywords: glutamine supplementation; infection; treatment visceral; miltefosine treatment ... See more keywords
Improved Milk Glutamine Level and Growth Performance of Suckling Piglets by Glutamine Supplementation in Maternal Diet
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DOI: 10.1515/aoas-2017-0040
Abstract: Abstract Glutamine plays an important role in neonatal growth and health. It is unknown whether supplementing the lactating sows’ diet with glutamine will benefit the growth performance and intestinal development of suckling piglets through increasing… read more here.
Keywords: milk; glutamine supplementation; suckling piglets; growth ... See more keywords
Glutamine Supplementation as an Anticancer Strategy: A Potential Therapeutic Alternative to the Convention
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DOI: 10.3390/cancers16051057
Abstract: Simple Summary Glutamine, vital for the body’s functions, is pivotal in cancer metabolism as it influences tumor growth. However, cancer cells’ complex adaptive metabolic dynamics raise concerns about potential limitations in glutamine antagonism strategies to… read more here.
Keywords: glutamine supplementation; cancer; tumor growth; potential therapeutic ... See more keywords
The Effect of Glutamine Supplementation on Ileum Histopathology of Rats with Acute and Chronic EPEC-Induced Diarrhea
Sign Up to like & getrecommendations! Published in 2020 at "Open Access Macedonian Journal of Medical Sciences"
DOI: 10.3889/oamjms.2020.3592
Abstract: BACKGROUND: Glutamine is a non-essential amino acid as the main fuel in the gastrointestinal mucosa. By its various gastrointestinal functions, glutamine is thought to increase the protection of the intestinal mucosa against local or systemic… read more here.
Keywords: glutamine supplementation; group; histopathology; diarrhea ... See more keywords