Polymer hydrogels for glutathione-mediated protein release
Sign Up to like & getrecommendations! Published in 2017 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2016.09.032
Abstract: Abstract The use of amine-terminated poly(ethylene glycol) star polymers as macroinitiators for the N-carboxyanhydride ring-opening polymerisation of S-tert-butylmercapto- l -cysteine N-carboxahydride is described to yield amphiphilic copolymers that are capable of forming discrete particles in… read more here.
Keywords: protein; hydrogels glutathione; polymer; glutathione mediated ... See more keywords
Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27165252
Abstract: The effectiveness of many anticancer drugs depends on the creation of specific metabolites that may alter their therapeutic or toxic properties. One significant route of biotransformation is a conjugation of electrophilic compounds with reduced glutathione,… read more here.
Keywords: anticancer drugs; glutathione mediated; conjugation anticancer; anticancer ... See more keywords