Heterodera schachtii glutathione peroxidase (HsGPx) is a parasitism protein
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Plant Diseases and Protection"
DOI: 10.1007/s41348-019-00256-2
Abstract: The beet cyst nematode (Heterodera schachtii) is a specialized obligate biotroph that is considered a major threat to sugar beet production. After infection, H. schachtii induce massive physiological and molecular changes to plant cells and… read more here.
Keywords: schachtii glutathione; peroxidase hsgpx; hsgpx; heterodera schachtii ... See more keywords
Comparison of analytical methods using enzymatic activity, immunoaffinity and selenium-specific mass spectrometric detection for the quantitation of glutathione peroxidase 1.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.01.068
Abstract: Glutathione peroxidase 1 (Gpx1), one of the most responsive selenoproteins to the variation of selenium concentration, is often used to evaluate "selenium status" at a cellular or organismal level. The four major types of analytical… read more here.
Keywords: detection; glutathione peroxidase; mass; selenium ... See more keywords
Screening for novel inhibitors of glutathione peroxidase
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.152
Abstract: Cancer cells have higher basal levels of reactive oxygen species (ROS) production, and altered expression of antioxidant enzymes, when compared to normal cells. At high levels, ROS can cause substantial cellular damage, often leading to… read more here.
Keywords: inhibitors glutathione; glutathione peroxidase; novel inhibitors; screening novel ... See more keywords
Role of glutathione peroxidase 1 in glucose and lipid metabolism‐related diseases
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.05.077
Abstract: ABSTRACT Glutathione peroxidase 1 (GPX1) is a selenium‐dependent enzyme that reduces intracellular hydrogen peroxide and lipid peroxides. While past research explored regulations of gene expression and biochemical function of this selenoperoxidase, GPX1 has recently been… read more here.
Keywords: metabolism related; glutathione peroxidase; gpx1; biology ... See more keywords
Study on antioxidant effect of recombinant glutathione peroxidase 1.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.12.183
Abstract: Glutathione peroxidase 1 (GPx1) is an important antioxidant selenium enzyme and has a good prospect for drug development. However, the expression of GPx1 requires a complex expression mechanism, which makes the drug development of recombinant… read more here.
Keywords: glutathione peroxidase; recombinant; antioxidant effect; effect ... See more keywords
Rational redesign of the active site of selenosubtilisin with strongly enhanced glutathione peroxidase activity
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Catalysis"
DOI: 10.1016/j.jcat.2017.12.006
Abstract: Abstract The search for a perfect model to mimic the properties of the selenoenzyme glutathione peroxidase (GPx) has inspired great interest. Rational design and redesign of the structure–function relationship has become an indispensable technique. In… read more here.
Keywords: site selenosubtilisin; redesign; glutathione peroxidase; active site ... See more keywords
The mitochondrial isoform glutathione peroxidase 3 (OsGPX3) is involved in ABA responses in rice plants.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2020.104029
Abstract: Different environmental conditions can lead plants to a condition termed oxidative stress, which is characterized by a disruption in the equilibrium between the production of reactive oxygen species (ROS) and antioxidant defenses. Glutathione peroxidase (GPX),… read more here.
Keywords: involved aba; mitochondrial isoform; glutathione peroxidase; peroxidase osgpx3 ... See more keywords
Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
Sign Up to like & getrecommendations! Published in 2017 at "Redox Biology"
DOI: 10.1016/j.redox.2017.01.021
Abstract: Synaptic loss and neuron death are the underlying cause of neurodegenerative diseases such as Alzheimer's disease (AD); however, the modalities of cell death in those diseases remain unclear. Ferroptosis, a newly identified oxidative cell death… read more here.
Keywords: forebrain neurons; gpx4biko mice; glutathione peroxidase; neurodegeneration ... See more keywords
Changes of lipid peroxidation and glutathione redox system, and expression of glutathione peroxidase regulatory genes as effect of short‐term aflatoxin B1 exposure in common carp
Sign Up to like & getrecommendations! Published in 2018 at "Toxicon"
DOI: 10.1016/j.toxicon.2018.02.003
Abstract: &NA; Lipid peroxidation, glutathione content, glutathione peroxidase activity and gene expression of transcription factors, glutathione peroxidase, glutathione synthetase and glutathione reductase was investigated in common carp liver. Short term (24 h) exposure of aflatoxin B1… read more here.
Keywords: glutathione peroxidase; exposure; glutathione; lipid peroxidation ... See more keywords
Peripheral levels of superoxide dismutase and glutathione peroxidase in youths in ultra-high risk for psychosis: a pilot study
Sign Up to like & getrecommendations! Published in 2017 at "CNS Spectrums"
DOI: 10.1017/s1092852917000803
Abstract: Introduction Oxidative stress has been documented in chronic schizophrenia and in the first episode of psychosis, but there are very little data on oxidative stress prior to the disease onset. Objective This work aimed to… read more here.
Keywords: risk; levels superoxide; glutathione peroxidase; ultra high ... See more keywords
Regulation of Tyrosinase Enzyme Activity by Glutathione Peroxidase Mimics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c02359
Abstract: Hydrogen peroxide plays a crucial role in the melanogenesis process by regulating the activity of the key melanin-forming enzyme tyrosinase, responsible for the browning of fruits, vegetables, and seafood. Therefore, a molecule with dual activities,… read more here.
Keywords: glutathione peroxidase; tyrosinase; inhibition; activity ... See more keywords