Glutathione-Responsive Polyhomocysteine Derivatives with Ultralow Toxicity toward Therapeutic Delivery.
Sign Up to like & getrecommendations! Published in 2025 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.5c01014
Abstract: Disulfide-containing synthetic polypeptides hold significant promise as biodegradable and biocompatible carriers for controlled drug and gene delivery, enabling triggered therapeutic release with reduced cytotoxicity. However, disulfide incorporation remains challenging, whether through direct polymerization of disulfide-containing… read more here.
Keywords: glutathione responsive; polyhomocysteine derivatives; delivery; drug ... See more keywords
Glutathione-Responsive Metal-Organic-Framework-Derived MnxOy/(A/R)TiO2 Nanoparticles for Enhanced Synergistic Sonodynamic/Chemodynamic/Immunotherapy.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.4c12304
Abstract: Despite the potential of sonodynamic therapy (SDT) in treating malignant tumors, the lack of effective sonosensitizers has limited its clinical implementation. In this study, we explored the relationship between the heteroatom doping concentration in metal-organic… read more here.
Keywords: glutathione responsive; immunotherapy; tumor; metal organic ... See more keywords
Glutathione responsive polymers and their application in drug delivery systems
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c6py01365a
Abstract: Materials which respond to biological cues are the subject of intense research interest due to their possible application in smart drug delivery vehicles. In particular, novel polymers which respond to biochemical differences between the extra-and… read more here.
Keywords: responsive polymers; drug delivery; gsh responsive; delivery ... See more keywords
Glutathione-responsive Nanoparticles for Optimized Cas9/sgRNA Gene Editing Delivery.
Sign Up to like & getrecommendations! Published in 2025 at "Current drug targets"
DOI: 10.2174/0113894501370119250409074208
Abstract: read more here.
Keywords: optimized cas9; glutathione responsive; nanoparticles optimized; cas9 sgrna ... See more keywords