Catanionic Surfactant Vesicles as a New Platform for probing Glycan-Protein Interactions.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced functional materials"
DOI: 10.1002/adfm.201706215
Abstract: Glycomics lags substantially behind proteomics and genomics in its ability to decipher and synthesize complex glycans. The slow progress in deciphering glycan interactions at a molecular level is in large part due to the absence… read more here.
Keywords: protein; glycan functionalized; surfactant vesicles; catanionic surfactant ... See more keywords
An overview of lectin–glycan interactions: a key event in initiating fungal infection and pathogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Microbiology"
DOI: 10.1007/s00203-018-1487-1
Abstract: Infections due to microfungi are of serious concern in many parts of the world. Many species of microfungi are known to cause systemic infection in human beings. Pathogenic microorganisms employ various molecular strategies for colonizing… read more here.
Keywords: lectin glycan; infection; overview lectin; pathogenesis ... See more keywords
Polyvalent Glycan Quantum Dots as a Multifunctional Tool for Revealing Thermodynamic, Kinetic, and Structural Details of Multivalent Lectin–Glycan Interactions
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c11111
Abstract: Multivalent lectin–glycan interactions (MLGIs) are widespread and vital for biology. Their binding biophysical and structural details are thus highly valuable, not only for the understanding of binding affinity and specificity mechanisms but also for guiding… read more here.
Keywords: polyvalent glycan; lectin glycan; multivalent lectin; structural details ... See more keywords
Stereoelectronic Effects in Stabilizing Protein–N-Glycan Interactions Revealed by Experiment and Machine Learning
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DOI: 10.1038/s41557-021-00646-w
Abstract: The energetics of protein–carbohydrate interactions, central to many life processes, cannot yet be manipulated predictably. This is mostly due to an incomplete quantitative understanding of the enthalpic and entropic basis of these interactions in aqueous… read more here.
Keywords: machine learning; glycan interactions; stereoelectronic effects; stabilizing protein ... See more keywords
Glycan–glycan interactions determine Leishmania attachment to the midgut of permissive sand fly vectors
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Science"
DOI: 10.1039/d0sc03298k
Abstract: Direct glycan–glycan interactions are increasingly implicated in survival and pathogenicity of bacteria. Here, we show that they can be exploited by protozoan parasites in their insect hosts. Force spectroscopy revealed that Leishmania promastigotes display a… read more here.
Keywords: sand fly; midgut; fly; glycan glycan ... See more keywords
Lectin-Glycan Interactions in Corneal Infection and Inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02338
Abstract: The cornea is an extraordinary component of vision that functions as the principal barrier to pathogens in the eye while allowing light transmission into the retina. Understanding the cellular and molecular mechanisms that maintain homeostasis… read more here.
Keywords: lectin glycan; interactions corneal; corneal infection; infection ... See more keywords