Glycan-Modified Peptides for Dual Inhibition of Human Immunodeficiency Virus Entry into Dendritic Cells and T Cells.
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DOI: 10.1021/acs.jmedchem.4c00116
Abstract: Dendritic cells (DCs) play a crucial role in HIV-1 infection of CD4+ T cells. DC-SIGN, a lectin expressed on the surface of DCs, binds to the highly mannosylated viral membrane protein gp120 to capture HIV-1… read more here.
Keywords: hiv; glycan modified; inhibition; virus entry ... See more keywords