Synthesis of 15N-labeled heterocycles via the cleavage of C-N bonds of anilines and glycine-15N.
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DOI: 10.1039/d1cc01734a
Abstract: A nitrogen replacement process that directly incorporates the 15N atom of glycine-15N into anilines was reported. The process involves a Csp2-N bond cleavage of anilines driven by dearomatization and a Csp3-N bond cleavage of glycine-15N… read more here.
Keywords: glycine 15n; synthesis 15n; cleavage; labeled heterocycles ... See more keywords