Serine-Glycine-One-Carbon Metabolism: The Hidden Achilles Heel of MYCN-Amplified Neuroblastoma?
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DOI: 10.1158/0008-5472.can-19-1816
Abstract: In this issue of Cancer Research, Xia and colleagues show that MYC-induced metabolic reprograming results in dependency on the serine-glycine-one-carbon (SGOC) metabolic pathway in neuroblastoma. This occurs through MYCN and ATF4 activation of the SGOC… read more here.
Keywords: serine glycine; one carbon; mycn amplified; glycine one ... See more keywords