Glycine Substitutions in Collagen Heterotrimers Alter Triple Helical Assembly.
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DOI: 10.1021/acs.biomac.6b01808
Abstract: Osteogenesis imperfecta typically results from missense mutations in the collagen genome where the required glycine residues are replaced with another amino acid. Many models have attempted to replicate the structure of mutated collagen on the… read more here.
Keywords: composition register; glycine substitutions; triple helix; helix ... See more keywords