Articles with "glycogen metabolism" as a keyword



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Hindbrain estrogen receptor regulation of ventromedial hypothalamic glycogen metabolism and glucoregulatory transmitter expression in the hypoglycemic male rat

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Published in 2019 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2019.03.053

Abstract: Estrogen receptor-alpha (ERα) and -beta (ERβ) occur in key elements of the brain gluco-homeostatic network in both sexes, including the hindbrain dorsal vagal complex (DVC), but the influence of distinct receptor populations on this critical… read more here.

Keywords: glycogen metabolism; glycogen; male; receptor ... See more keywords
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Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.

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Published in 2021 at "Nature"

DOI: 10.1038/s41586-021-04019-8

Abstract: Adipocytes increase energy expenditure in response to prolonged sympathetic activation via persistent expression of uncoupling protein 1 (UCP1)1,2. Here we report that the regulation of glycogen metabolism by catecholamines is critical for UCP1 expression. Chronic β-adrenergic… read more here.

Keywords: metabolism; ucp1 expression; glycogen metabolism; glycogen ... See more keywords
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Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation.

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Published in 2023 at "Cell reports"

DOI: 10.2139/ssrn.4229509

Abstract: Chondrosarcomas are the most common malignancy of cartilage and are associated with somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 genes. Somatic IDH mutations are also found in its benign precursor lesion, enchondromas, suggesting… read more here.

Keywords: glycogen metabolism; idh1; mutant idh; cartilage ... See more keywords
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Genetic Variants of Glycogen Metabolism Genes Were Associated With Liver PDFF Without Increasing NAFLD Risk

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.830445

Abstract: Background/Aims: The storage amount of liver glycogen could affect the liver fibrosis assessment made by MRI-based methods. However, it remained unclear whether glycogen amount could bias the estimation of liver fat content by proton density… read more here.

Keywords: genes associated; glycogen metabolism; glycogen; metabolism genes ... See more keywords
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Identification of the Genes Related to the Glycogen Metabolism in Hyperthermophilic Archaeon, Sulfolobus acidocaldarius

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Published in 2021 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2021.661053

Abstract: Glycogen is a polysaccharide that comprises α-1,4-linked glucose backbone and α-1,6-linked glucose polymers at the branching points. It is widely found in organisms ranging from bacteria to eukaryotes. The physiological role of glycogen is not… read more here.

Keywords: glycogen content; glycogen metabolism; glycogen; strain ... See more keywords
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Glycogen Metabolism Predicts the Efficacy of Immunotherapy for Urothelial Carcinoma

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Published in 2021 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2021.723066

Abstract: Urothelial cancer (UC) is one of the common refractory tumors and chemotherapy is the primary treatment for it. The advent of immune checkpoint inhibitors (ICI) has facilitated the development of treatment strategies for UC patients.… read more here.

Keywords: gms; glycogen metabolism; treatment; gms patients ... See more keywords
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Dysferlin Deficiency Results in Myofiber-Type Specific Differences in Abundances of Calcium-Handling and Glycogen Metabolism Proteins

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24010076

Abstract: Dysferlinopathies are a clinically heterogeneous group of muscular dystrophies caused by a genetic deficiency of the membrane-associated protein dysferlin, which usually manifest post-growth in young adults. The disease is characterized by progressive skeletal muscle wasting… read more here.

Keywords: dysferlin deficiency; deficiency; myofiber type; glycogen metabolism ... See more keywords
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Effects of Thiamin Restriction on Exercise-Associated Glycogen Metabolism and AMPK Activation Level in Skeletal Muscle

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Published in 2022 at "Nutrients"

DOI: 10.3390/nu14030710

Abstract: This study aimed to investigate the direct influence of a decrease in the cellular thiamin level, before the onset of anorexia (one of the symptoms of thiamin deficiency) on glycogen metabolism and the AMP-activated protein… read more here.

Keywords: glycogen metabolism; muscle; level; ampk activation ... See more keywords