Diagnostic accuracy of glycogen phosphorylase BB for myocardial infarction: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24368
Abstract: We tried to investigate the diagnostic accuracy of glycogen phosphorylase BB as a cardiac marker for myocardial infarction. read more here.
Keywords: glycogen phosphorylase; accuracy glycogen; myocardial infarction; diagnostic accuracy ... See more keywords
A new interpretation of sulfate activation of rabbit muscle glycogen phosphorylase
Sign Up to like & getrecommendations! Published in 2018 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-018-9823-x
Abstract: It is widely known that sulfate ion at high concentration serves like an allosteric activator of glycogen phosphorylase (GP). Based on the crystallographic studies on GP, it has been assumed that the sulfate ion is… read more here.
Keywords: sulfate; high concentration; glycogen; glycogen phosphorylase ... See more keywords
Knockdown of glycogen phosphorylase and glycogen synthase influences expression of chitin synthesis genes of rice brown planthopper Nilaparvata lugens
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Asia-Pacific Entomology"
DOI: 10.1016/j.aspen.2019.06.006
Abstract: Abstract Glycogen synthase (GS) and glycogen phosphorylase (GP) are two key enzymes in the glycogen synthesis pathway, which catalyze trehalose and glucose transformation in insects. GS and GP can be regulated by trehalose metabolism, which… read more here.
Keywords: glycogen phosphorylase; chitin; chitin synthesis; glycogen ... See more keywords
Mechanism of aggregation of UV-irradiated glycogen phosphorylase b at a low temperature in the presence of crowders and trimethylamine N-oxide.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2017.10.001
Abstract: To characterize the initial stages of protein aggregation, the kinetics of aggregation of UV-irradiated glycogen phosphorylase b (UV-Phb) was studied under conditions when the aggregation proceeded at a low rate (10°C, 0.03M Hepes buffer, pH6.8,… read more here.
Keywords: aggregation; irradiated glycogen; mechanism; presence ... See more keywords
Studies on the reversible enzyme reaction of rabbit muscle glycogen phosphorylase b using isothermal titration calorimetry.
Sign Up to like & getrecommendations! Published in 2019 at "Carbohydrate research"
DOI: 10.1016/j.carres.2019.03.014
Abstract: Glycogen phosphorylase enzymes (GP) catalyse reversible reactions; the glucose transfer from glycogen to inorganic phosphate (Pi, phosphorolysis) or the reverse glucose transfer from glucose-1-phosphate (G-1-P) to glycogen (synthesis). Rabbit muscle GPb (rmGPb) was used as… read more here.
Keywords: reversible enzyme; glycogen; glycogen phosphorylase; rabbit muscle ... See more keywords
Effects of phosphorylation on the activity of glycogen phosphorylase in mutton during incubation at 4 °C in vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.126162
Abstract: The aim of this study was to assess the effects of the phosphorylation levels of glycogen phosphorylase on its activity in mutton sarcoplasmic protein samples during incubation at 4 °C. Samples of sarcoplasmic proteins from mutton… read more here.
Keywords: incubation; activity; glycogen phosphorylase; phosphorylase ... See more keywords
van der Waals interactions govern C-β-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2017.05.001
Abstract: 3-(C-Glucopyranosyl)-5aryl-1,2,4-triazoles with an aryl moiety larger than phenyl have been shown to have strong inhibitory potency (Ki values in the range of upper nM) for human liver glycogen phosphorylase (hlGP), a pharmacologically relevant target for… read more here.
Keywords: van der; potency; liver glycogen; glycogen phosphorylase ... See more keywords
Allosteric Regulation of Glycogen Phosphorylase by Order/Disorder Transition of the 250′ and 280s Loops
Sign Up to like & getrecommendations! Published in 2023 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00671
Abstract: Allostery is a fundamental mechanism of protein activation, yet the precise dynamic changes that underlie functional regulation of allosteric enzymes, such as glycogen phosphorylase (GlyP), remain poorly understood. Despite being the first allosteric enzyme described,… read more here.
Keywords: allosteric regulation; glyp; 250 280s; glycogen phosphorylase ... See more keywords
Novel Liver-targeted conjugates of Glycogen Phosphorylase Inhibitor PSN-357 for the Treatment of Diabetes: Design, Synthesis, Pharmacokinetic and Pharmacological Evaluations
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42251
Abstract: PSN-357, an effective glycogen phosphorylase (GP) inhibitor for the treatment for type 2 diabetics, is hampered in its clinical use by the poor selectivity between the GP isoforms in liver and in skeletal muscle. In… read more here.
Keywords: glycogen phosphorylase; phosphorylase inhibitor; liver targeted; psn 357 ... See more keywords
Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase.
Sign Up to like & getrecommendations! Published in 2018 at "Current drug discovery technologies"
DOI: 10.2174/1570163814666170619091736
Abstract: BACKGROUND Glycogen phosphorylase (GP) is a pharmaceutical target for the discovery of new antihyperglycaemic agents. Punica granatum is a well-known plant for its potent antioxidant and antimicrobial activities but so far has not been examined… read more here.
Keywords: punica granatum; glycogen phosphorylase; industrial juicing; affinity crystallography ... See more keywords
Mechanochemical Promoted Heterocycles: A Solvent-Free Route to Triazole Carbohydrates as Glycogen Phosphorylase Inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Current organic synthesis"
DOI: 10.2174/1570179419666220420133644
Abstract: AIMS This study aimed to recommend a novel way for the preparation of carbohydrates containing triazole derivatives. BACKGROUND Triazoles containing derivatives have numerous biological activities. Ball milling is a fast, modest, green process with massive… read more here.
Keywords: glycogen phosphorylase; triazole; phosphorylase inhibitors; reaction ... See more keywords