Production of heparin and λ-carrageenan anti-heparanase derivatives using a combination of physicochemical depolymerization and glycol splitting.
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DOI: 10.1016/j.carbpol.2017.02.040
Abstract: Strongly associated with tumor angiogenesis and metastasis, the enzyme heparanase is an endo-β-d-glucuronidase which is overexpressed in the tumor microenvironment. Its inhibition could be one of the most promising anti-angiogenic approaches to date. Although heparin… read more here.
Keywords: heparanase; heparin; anti heparanase; glycol splitting ... See more keywords