N6-methyladenosine regulates glycolysis of cancer cells through PDK4
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16306-5
Abstract: Studies on biological functions of N6-methyladenosine (m6A) modification in mRNA have sprung up in recent years. We find m6A can positively regulate the glycolysis of cancer cells. Specifically, m6A-sequencing and functional studies confirm that pyruvate… read more here.
Keywords: pdk4; regulates glycolysis; cancer cells; cancer ... See more keywords
Molecular intricacies of aerobic glycolysis in cancer: current insights into the classic metabolic phenotype
Sign Up to like & getrecommendations! Published in 2018 at "Critical Reviews in Biochemistry and Molecular Biology"
DOI: 10.1080/10409238.2018.1556578
Abstract: Abstract Aerobic glycolysis is the process of oxidation of glucose into pyruvate followed by lactate production under normoxic condition. Distinctive from its anaerobic counterpart (i.e. glycolysis that occurs under hypoxia), aerobic glycolysis is frequently witnessed… read more here.
Keywords: molecular intricacies; glycolysis; intricacies aerobic; aerobic glycolysis ... See more keywords