The type 1 transmembrane glycoprotein B7‐H3 interacts with the glycolytic enzyme ENO1 to promote malignancy and glycolysis in HeLa cells
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13164
Abstract: The role of the type 1 transmembrane glycoprotein B7‐H3 is controversial in tumorigenesis; thus, a better clarification of its involvement in cancer is crucial. In the present study, 79.3% of cervical cancer samples were found… read more here.
Keywords: glycolysis; type transmembrane; transmembrane glycoprotein; hela ... See more keywords
The Glycolytic Enzyme PFKFB3 Controls TNF-α-Induced Endothelial Proinflammatory Responses
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DOI: 10.1007/s10753-018-0880-x
Abstract: Endothelial cells play an important role in health and a variety of diseases. Recent evidences show that endothelial cells rely on glycolysis rather than on oxidative phosphorylation to generate energy to support cellular functions such… read more here.
Keywords: pfkfb3; tnf induced; endothelial cells; enzyme pfkfb3 ... See more keywords
The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferation.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2209435120
Abstract: Aberrantly upregulated choline phospholipid metabolism is a novel emerging hallmark of cancer, and choline kinase α (CHKα), a key enzyme for phosphatidylcholine production, is overexpressed in many types of human cancer through undefined mechanisms. Here,… read more here.
Keywords: choline phospholipid; metabolism; phospholipid metabolism; glycolytic enzyme ... See more keywords
Protein kinase activity of the glycolytic enzyme PGK1 regulates autophagy to promote tumorigenesis
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DOI: 10.1080/15548627.2017.1313945
Abstract: ABSTRACT Macroautophagy/autophagy is a cellular defense response to stress conditions and is crucial for cell homeostasis maintenance. However, the precise mechanism underlying autophagy initiation, especially in response to glutamine deprivation and hypoxia, is yet to… read more here.
Keywords: pgk1; glycolytic enzyme; activity; protein kinase ... See more keywords