Hitting the sweet spot with capillary electrophoresis: advances in N-glycomics and glycoproteomics.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2021.07.013
Abstract: N-glycosylation is of paramount importance for understanding the mechanisms of various human diseases and ensuring the safety and efficacy of biotherapeutics. Traditional glycan analysis techniques include LC-based separations and MALDI-TOF-MS identification. However, the current state-of-the-art… read more here.
Keywords: capillary electrophoresis; hitting sweet; sweet spot; glycomics glycoproteomics ... See more keywords
Advancement in Clinical Glycomics and Glycoproteomics for Congenital Disorders of Glycosylation: Progress and Challenges Ahead
Sign Up to like & getrecommendations! Published in 2025 at "Biomedicines"
DOI: 10.3390/biomedicines13081964
Abstract: Congenital disorders of glycosylation (CDG) are a group of rare, multisystemic genetic diseases caused by defects in glycan biosynthesis and protein glycosylation. Their broad clinical and genetic heterogeneity often require advanced diagnostic strategies. Clinical glycomics… read more here.
Keywords: disorders glycosylation; glycosylation; advancement clinical; glycomics glycoproteomics ... See more keywords