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Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200292
Abstract: Advances in bioanalytical technology have accelerated the analysis of complex protein glycosylation, which is beneficial to understanding glycosylation in drug discovery and disease diagnosis. Due to its biological uniqueness in the course of disease occurrence…
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Keywords:
protein glycosylation;
glycopeptide enrichment;
enrichment methods;
analysis ... See more keywords
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Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-02427-9
Abstract: Highly specific enrichment of N-linked glycopeptides from complex biological samples is crucial prior to mass spectrometric analysis. In this work, a hydrophilic metal–organic framework composite is prepared by the growth of UiO-66-NH 2 on graphene…
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Keywords:
enrichment;
microscopy;
linked glycopeptide;
glycopeptide enrichment ... See more keywords
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Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.1091243
Abstract: The comprehensive profiling of glycoproteins is of great significance for the timely clinical diagnosis and therapy. However, inherent obstacles hamper their direct analysis from biological samples, and specific enrichment prior to analysis is indispensable. Among…
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Keywords:
glycopeptide enrichment;
organic frameworks;
hydrophilic mofs;
metal organic ... See more keywords