The role of the dystrophin glycoprotein complex on the neuromuscular system
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.134833
Abstract: The Dystrophin Glycoprotein Complex (DGC) is a large multi-protein complex that links cytoskeleton actin to the extracellular matrix. This complex is critical in maintaining the structural integrity of muscle fibers and the stability of the… read more here.
Keywords: role dystrophin; dystrophin glycoprotein; glycoprotein complex; complex neuromuscular ... See more keywords
Enhancement of guinea pig cytomegalovirus infection by two endogenously expressed components of the pentameric glycoprotein complex in epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-65545-5
Abstract: A better understanding of the mechanisms underlying cell tropisms and the efficiency of viral infection is critical for the development of vaccines and antiviral drugs for viral diseases. In this study, we worked on the… read more here.
Keywords: guinea pig; pentameric glycoprotein; infection; viral infection ... See more keywords
Lassa virus glycoprotein complex review: insights into its unique fusion machinery
Sign Up to like & getrecommendations! Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20211930
Abstract: Abstract Lassa virus (LASV), an arenavirus endemic to West Africa, causes Lassa fever—a lethal hemorrhagic fever. Entry of LASV into the host cell is mediated by the glycoprotein complex (GPC), which is the only protein… read more here.
Keywords: fusion; lassa virus; glycoprotein complex; host cell ... See more keywords
The Pentamer glycoprotein complex inhibits viral Immediate Early transcription during Human Cytomegalovirus infections
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2408078121
Abstract: Significance The Pentamer glycoprotein complex plays a crucial role in Human Cytomegalovirus (HCMV) infections by shaping its tropism and serving as a target for both natural and vaccine-induced antiviral responses. Uncovering all the biological functions… read more here.
Keywords: immediate early; human cytomegalovirus; pentamer glycoprotein; viral immediate ... See more keywords
Distinct roles of the dystrophin-glycoprotein complex: α-dystrobrevin and α-syntrophin in the maintenance of the postsynaptic apparatus of the neuromuscular synapse.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac041
Abstract: α-syntrophin (α-syn) and α-dystrobrevin (α-dbn), two components of the dystrophin-glycoprotein complex, are essential for the maturation and maintenance of the neuromuscular junction (NMJ) and mice deficient in either α-syn or α-dbn exhibit similar synaptic defects.… read more here.
Keywords: dbn; dbn syn; dystrophin glycoprotein; syn ... See more keywords
Value of muscle magnetic resonance imaging in the differential diagnosis of muscular dystrophies related to the dystrophin-glycoprotein complex
Sign Up to like & getrecommendations! Published in 2019 at "Orphanet Journal of Rare Diseases"
DOI: 10.1186/s13023-019-1242-y
Abstract: Dystrophin-glycoprotein complex (DGC)-related muscular dystrophies may present similar clinical and pathological features as well as undetectable mutations thus being sometimes difficult to distinguish. We investigated the value of muscle magnetic resonance imaging (MRI) in the… read more here.
Keywords: dystrophin glycoprotein; muscle; muscle magnetic; value muscle ... See more keywords