Structures of full-length glycoprotein hormone receptor signalling complexes.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03924-2
Abstract: Luteinizing hormone and chorionic gonadotropin are glycoprotein hormones that are related to follicle-stimulating hormone and thyroid-stimulating hormone1,2. Luteinizing hormone and chorionic gonadotropin are essential to human reproduction and are important therapeutic drugs3-6. They activate the… read more here.
Keywords: receptor; hormone; transmembrane domain; glycoprotein hormone ... See more keywords
Unconventional Actions of Glycoprotein Hormone Subunits: A Comprehensive Review
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.731966
Abstract: The glycoprotein hormones (GPH) are heterodimers composed of a common α subunit and a specific β subunit. They act by activating specific leucine-rich repeat G protein-coupled receptors. However, individual subunits have been shown to elicit… read more here.
Keywords: actions glycoprotein; hormone subunits; unconventional actions; review ... See more keywords