ERBB and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13318
Abstract: Chemotherapy resistance is a persistent clinical problem in relapsed high‐risk neuroblastomas. We tested a panel of 15 drugs for sensitization of neuroblastoma cells to the conventional chemotherapeutic vincristine, identifying tariquidar, an inhibitor of the transmembrane… read more here.
Keywords: inhibitors break; erbb glycoprotein; glycoprotein; glycoprotein inhibitors ... See more keywords
Abstract 3068: The glycoprotein inhibitors overcome the resistance of the topoisomerase inhibitors in small cell lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-3068
Abstract: Small cell lung cancer (SCLC) is a highly aggressive disease with median survival of RNA sequencing was performed using the established cell lines to discover novel therapeutic targets associated with the resistance to topoisomerase inhibitors.… read more here.
Keywords: topoisomerase inhibitors; glycoprotein inhibitors; resistance topoisomerase; cancer ... See more keywords