7-Fluorosialyl Glycosides Are Hydrolysis Resistant but Readily Assembled by Sialyltransferases Providing Easy Access to More Metabolically Stable Glycoproteins
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DOI: 10.1021/acscentsci.0c01589
Abstract: The maintenance of therapeutic glycoproteins within the circulatory system is associated, in large part, with the integrity of sialic acids as terminal sugars on the glycans. Glycoprotein desialylation, either by spontaneous cleavage or through host… read more here.
Keywords: glycosides hydrolysis; hydrolysis resistant; hydrolysis; fluorosialyl glycosides ... See more keywords