Synthesis of novel glycosyl-1,2,3-1H-triazolyl methyl quinazolin-4(3H)-ones and their effect on GLUT4 translocation
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DOI: 10.1016/j.tet.2016.11.074
Abstract: Cu(OTf)2 catalyzed synthesis of propargylated 2,3-dihydroquinazolin-4(1H)-ones has been accomplished from 2-amino-N-propargyl benzamides and aromatic aldehydes under MW irradiation. Next, a series of novel glycosyl triazolyl methyl quinazolin-4(3H)-ones have been synthesized by CuAAC reaction of propargylated… read more here.
Keywords: novel glycosyl; glut4 translocation; triazolyl methyl; quinazolin ones ... See more keywords