Shear force sensing of epithelial Na+ channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaC
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DOI: 10.1073/pnas.1911243117
Abstract: Significance The ability to sense mechanical forces is essential for all living organisms. Extracellular tethers have been proposed to mediate mechanical activation of channels belonging to the epithelial Na+ channel (ENaC)/degenerin protein family. The nature… read more here.
Keywords: blood pressure; force; glycosylated asparagines; enac ... See more keywords