Articles with "glycosylated pillar" as a keyword



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Supramolecular nanoprodrug based on a chloride channel blocker and glycosylated pillar[5]arenes for targeted chemoresistance cancer therapy.

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Published in 2023 at "Chemical communications"

DOI: 10.1039/d3cc00233k

Abstract: A supramolecular nanoprodrug (DOX@GP5⊃Pro-NFA) was constructed based on the host-guest complexation of chloride channel blocker prodrug (Pro-NFA) and glycosylated pillar[5]arene (GP5), which could target tumor cells via galactose and release DOX/NFA responsively under esterase stimulation.… read more here.

Keywords: supramolecular nanoprodrug; channel blocker; chloride channel; glycosylated pillar ... See more keywords