Global evolution of glycosylated polyene macrolide antibiotic biosynthesis.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular phylogenetics and evolution"
DOI: 10.1016/j.ympev.2018.06.005
Abstract: Antibiotics are the most marvelous evolutionary products of microbes to obtain competitive advantage and maintain ecological balance. However, the origination and development of antibiotics has yet to be explicitly investigated. Due to diverse structures and… read more here.
Keywords: biosynthesis; evolution; polyene macrolide; global evolution ... See more keywords
New Glycosylated Polyene Macrolides: Refining the Ore from Genome Mining
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11030334
Abstract: Glycosylated polyene macrolides include effective antifungal agents, such as pimaricin, nystatin, candicidin, and amphotericin B. For the treatment of systemic mycoses, amphotericin B has been described as a gold-standard antibiotic because of its potent activity… read more here.
Keywords: polyene macrolides; polyene; genome; glycosylated polyene ... See more keywords