Precise O-Glycosylation Site Localization of CD24Fc by LC-MS Workflows.
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DOI: 10.1021/acs.analchem.2c01137
Abstract: CD24Fc is a homodimeric recombinant Fc-fusion protein comprised of human CD24 connected to immunoglobulin G1 (IgG1) Fc fragment. CD24 is heavily glycosylated, and its biological function is considered mainly mediated by its glycosylation. Identification of… read more here.
Keywords: glycosylation site; precise glycosylation; glycosylation; glycosylation sites ... See more keywords
Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains
Sign Up to like & getrecommendations! Published in 2017 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1712377114
Abstract: Significance The majority of influenza vaccine antigens are prepared in chicken eggs. Human vaccine strains grown in eggs often possess adaptive mutations that increase viral attachment to chicken cells. Most of these adaptive mutations are… read more here.
Keywords: glycosylation site; vaccine; h3n2; egg adapted ... See more keywords
OPN N-glycosylation Promoted Bone Destruction.
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DOI: 10.1111/odi.14218
Abstract: OBJECTIVES Exploring the role of OPN N-glycosylation in osteoblasts and osteoclasts. METHODS Immunohistochemistry was used to detect the expression of OPN in mice with apical periodontitis. The asparagine at position 79 of the OPN protein… read more here.
Keywords: expression; opn glycosylation; glycosylation; glycosylation opn ... See more keywords
Emerging of H5N6 Subtype Influenza Virus with 129-Glycosylation Site on Hemagglutinin in Poultry in China Acquires Immune Pressure Adaption
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DOI: 10.1128/spectrum.02537-21
Abstract: H5N6 avian influenza viruses (AIVs) were first reported in 2013 and have spread throughout many countries. In China, compulsory vaccine inoculation has been adopted to control H5 subtype avian influenza. ABSTRACT For an investigation into… read more here.
Keywords: glycosylation site; influenza; h5n6 aivs; glycosylation ... See more keywords
Glycosylation at 11Asn on hemagglutinin of H5N1 influenza virus contributes to its biological characteristics
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DOI: 10.1186/s13567-017-0484-8
Abstract: A stem glycosylation site of hemagglutinin (HA) is important to the stability of the HA trimmer. A previous study shows that the stem 10/11 overlap glycosylation site of the H5 subtype avian influenza virus may… read more here.
Keywords: rsy; influenza virus; glycosylation; glycosylation site ... See more keywords
Structural analysis of human glycoprotein butyrylcholinesterase using atomistic molecular dynamics: The importance of glycosylation site ASN241
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DOI: 10.1371/journal.pone.0187994
Abstract: Human butyrylcholinesterase (BChE) is a glycoprotein capable of bioscavenging toxic compounds such as organophosphorus (OP) nerve agents. For commercial production of BChE, it is practical to synthesize BChE in non–human expression systems, such as plants… read more here.
Keywords: butyrylcholinesterase; glycosylation site; site; site asn241 ... See more keywords