Determinants for Substrate Recognition in the Glycyl Radical Enzyme Benzylsuccinate Synthase Revealed by Targeted Mutagenesis
Sign Up to like & getrecommendations! Published in 2021 at "ACS Catalysis"
DOI: 10.1021/acscatal.0c04954
Abstract: Anaerobic toluene degradation is initiated by adding toluene to fumarate via the glycyl radical enzyme benzylsuccinate synthase (BSS). We developed a recombinant production system producing active ... read more here.
Keywords: radical enzyme; benzylsuccinate synthase; enzyme benzylsuccinate; glycyl radical ... See more keywords
A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-l-proline
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DOI: 10.1126/science.aai8386
Abstract: Chemically guided functional profiling The big challenge posed by the microbiota living in or on humans is working out what they do for us. Microorganisms generate large quantities of peptides and proteins that may have… read more here.
Keywords: human gut; chemistry; enzyme; trans hydroxy ... See more keywords
Characterization of a Glycyl Radical Enzyme Bacterial Microcompartment Pathway in Rhodobacter capsulatus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bacteriology"
DOI: 10.1128/jb.00343-18
Abstract: BMCs are protein shells that are designed to compartmentalize enzymatic reactions that require either sequestration of a substrate or the sequestration of toxic intermediates. Due to their ability to compartmentalize reactions, BMCs have also become… read more here.
Keywords: microcompartment; biochemistry; glycyl radical; radical enzyme ... See more keywords