Stability characteristics of O/W emulsions prepared using purified glycyrrhizin or a non-purified glycyrrhizin-rich extract from liquorice root (Glycyrrhiza glabra)
Sign Up to like & getrecommendations! Published in 2020 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2020.126006
Abstract: Abstract This study evaluated the stability characteristics of oil-in-water emulsions prepared using purified glycyrrhizin (PG) or a non-purified glycyrrhizin-rich extract from liquorice root (LRE) at equivalent glycyrrhizin concentrations (0.01−0.1%, w/w). PG-stabilized emulsions were sensitive to… read more here.
Keywords: glycyrrhizin; emulsions prepared; stability characteristics; prepared using ... See more keywords
Purification and characterization of a novel β-glucuronidase precisely converts glycyrrhizin to glycyrrhetinic acid 3-O-mono-β-D-glucuronide from plant endophytic Chaetomium globosum DX-THS3.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.05.047
Abstract: Glycyrrhetinic acid monoglucuronide (GAMG) is an innovative functional sweetener with higher sweetness and stronger pharmacological activity than glycyrrhizin (GL). A novel β-glucuronidase (cg-GUS) was firstly screened from plant endophytic fungus Chaetomium globosum DX-THS3. The cg-GUS… read more here.
Keywords: glycyrrhetinic acid; plant endophytic; glycyrrhizin; glucuronidase ... See more keywords
Glycyrrhizin inhibits LPS-induced inflammatory mediator production in endometrial epithelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.05.032
Abstract: Endometriosis is a continuous inflammation of uterine endometrium that usually affects women of reproductive age. Glycyrrhizin, a triterpene isolated from the roots and rhizomes of licorice (Glycyrrhiza glabra), has been known to have anti-inflammatory effect.… read more here.
Keywords: epithelial cells; lps induced; production; glycyrrhizin ... See more keywords
Glycyrrhizin Attenuates the Process of Epithelial-to-Mesenchymal Transition by Modulating HMGB1 Initiated Novel Signaling Pathway in Prostate Cancer Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b00251
Abstract: High mobility group box 1 (HMGB1) is upregulated in nearly every tumor type. Importantly, clinical evidence also proposed that HMGB1 is particularly increased in metastatic prostate cancer patients. Besides, a growing number of studies highlighted… read more here.
Keywords: hmgb1; glycyrrhizin; prostate cancer; cancer cells ... See more keywords
Liposome-encapsulated glycyrrhizin alleviates hyperglycemia and glycation-induced iron-catalyzed oxidative reactions in streptozotocin-induced diabetic rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Liposome Research"
DOI: 10.1080/08982104.2022.2036756
Abstract: Abstract Glycyrrhizin, a bioactive constituent of Glycyrrhiza glabra has been reported to ameliorate diabetes. Here, the effects of liposome-encapsulated glycyrrhizin on STZ-induced diabetes and associated oxidative stress were investigated. Wistar rats were grouped as control… read more here.
Keywords: encapsulated glycyrrhizin; iron; dtg; dtbd ... See more keywords
Glycyrrhizin ameliorates impaired glucose metabolism and ovarian dysfunction in a polycystic ovary syndrome mouse model.
Sign Up to like & getrecommendations! Published in 2023 at "Biology of reproduction"
DOI: 10.1093/biolre/ioad048
Abstract: OBJECTIVE The aim of this study was to determine the impact of glycyrrhizin, an inhibitor of high mobility group box 1 (HMGB1), on glucose metabolic disorders and ovarian dysfunction in mice with polycystic ovary syndrome… read more here.
Keywords: polycystic ovary; ovary syndrome; pcos; mice ... See more keywords
Glycyrrhizin, an HMGB1 inhibitor, exhibits neuroprotective effects in rats after lithium‐pilocarpine‐induced status epilepticus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.13040
Abstract: It has been proven that extracellular HMGB1 is involved in progression of neurologic disorders, such as stroke, traumatic brain injury, meningitis and epilepsy. Glycyrrhizin (GL) is a direct inhibitor of HMGB1, and blocks HMGB1 release… read more here.
Keywords: neuroprotective effects; pilocarpine induced; glycyrrhizin; status epilepticus ... See more keywords
Abstract 2334: Reprogramming M2-like tumor associated macrophages using a natural compound, glycyrrhizin, as a potential therapeutic strategy against prostate cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2334
Abstract: Tumor Associated Macrophages (TAMs), copiously found in the Tumor Microenvironment (TME) are key players in creating an immunosuppressive environment, increasing angiogenesis and metastasis in prostate cancer (PCa). They are plastic in nature and usually exist… read more here.
Keywords: glycyrrhizin treated; associated macrophages; glycyrrhizin; cancer ... See more keywords
Symptomatic Protective Action of Glycyrrhizin (Licorice) in COVID-19 Infection?
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DOI: 10.3389/fimmu.2020.01239
Abstract: The role of the ACE2 enzyme in the COVID-19 infection is 2-fold, with opposing implications for the disease development. 1. The membrane bound angiotensin converting enzyme 2 (ACE2) serves as the entry point of COVID-19… read more here.
Keywords: anti inflammatory; glycyrrhizin; infection; covid ... See more keywords
Antifibrotic Effects of High-Mobility Group Box 1 Protein Inhibitor (Glycyrrhizin) on Keloid Fibroblasts and Keloid Spheroids through Reduction of Autophagy and Induction of Apoptosis
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20174134
Abstract: Overabundance of extracellular matrix resulting from hyperproliferation of keloid fibroblasts (KFs) and dysregulation of apoptosis represents the main pathophysiology underlying keloids. High-mobility group box 1 (HMGB1) plays important roles in the regulation of cellular death.… read more here.
Keywords: hmgb1; apoptosis; glycyrrhizin; treatment ... See more keywords