LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "glyoxalase" as a keyword



Photo by cdc from unsplash

Spectrophotometric Method for Determining Glyoxalase 1 Activity in Cerebral Cavernous Malformation (CCM) Disease.

Sign Up to like & get
recommendations! Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0640-7_33

Abstract: Glyoxalase 1 (Glo1) is a glutathione (GSH)-dependent enzyme that catalyzes the isomerization of the hemithioacetal formed non-enzymatically from methylglyoxal (MG) and GSH to S-D-lactoylglutathione (SLG). The activity of Glo1 is measured spectrophotometrically by following the… read more here.

Keywords: glyoxalase; ccm disease; malformation ccm; cerebral cavernous ... See more keywords
Photo by cdc from unsplash

Inducible knockdown of Mycobacterium smegmatis MSMEG_2975 (glyoxalase II) affected bacterial growth, antibiotic susceptibility, biofilm, and transcriptome

Sign Up to like & get
recommendations! Published in 2021 at "Archives of Microbiology"

DOI: 10.1007/s00203-021-02652-5

Abstract: Tuberculosis (TB) causes millions of deaths each year across the globe. Multiple drug-resistant (MDR) and extensively drug-resistant (XDR) mycobacterial strains have made the treatment extremely difficult. To overcome this hurdle, the development of new drug… read more here.

Keywords: inducible knockdown; mycobacterium smegmatis; glyoxalase; msmeg 2975 ... See more keywords
Photo by liammcgarry from unsplash

Ectopic expression of DJ-1/PfpI domain containing Erianthus arundinaceus Glyoxalase III (EaGly III) enhances drought tolerance in sugarcane

Sign Up to like & get
recommendations! Published in 2020 at "Plant Cell Reports"

DOI: 10.1007/s00299-020-02585-1

Abstract: Key message Sugarcane transgenic overexpressing EaGly III from Erianthus arundinaceus showed enhanced water deficit stress tolerance. Abstract Methylglyoxal (MG), an α-ketoaldehyde formed from either glycolysis or TCA cycle, is capable of causing total cellular damage… read more here.

Keywords: glyoxalase; tolerance; sugarcane; erianthus arundinaceus ... See more keywords
Photo by sharonmccutcheon from unsplash

γ-aminobutyric acid (GABA) confers chromium stress tolerance in Brassica juncea L. by modulating the antioxidant defense and glyoxalase systems

Sign Up to like & get
recommendations! Published in 2017 at "Ecotoxicology"

DOI: 10.1007/s10646-017-1800-9

Abstract: Chromium (Cr) toxicity is hazardous to the seed germination, growth, and development of plants. γ-aminobutyric acid (GABA) is a non-protein amino acid and is involved in stress tolerance in plants. To investigate the effects of… read more here.

Keywords: glyoxalase; acid gaba; content; gaba ... See more keywords
Photo by richardrschunemann from unsplash

Limonene protects osteoblasts against methylglyoxal-derived adduct formation by regulating glyoxalase, oxidative stress, and mitochondrial function.

Sign Up to like & get
recommendations! Published in 2017 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2017.10.001

Abstract: Methylglyoxal (MG) is a potent protein glycating agent and an important precursor of advanced glycation end products, which are involved in the pathogenesis of diabetic osteopathy. In this study, we investigated the effects of limonene… read more here.

Keywords: glyoxalase; adduct formation; limonene protects; limonene ... See more keywords
Photo by nci from unsplash

Galangin induces cell death by modulating the expression of glyoxalase-1 and Nrf-2 in HeLa cells.

Sign Up to like & get
recommendations! Published in 2018 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2017.11.001

Abstract: The present study was designed to understand the anticancer property and molecular mechanisms associated with chemo preventive effects of galangin. The anticancer effect was evaluated in vitro using human cervical cancer cell line (HeLa). Galangin… read more here.

Keywords: induces cell; glyoxalase; galangin induces; hela ... See more keywords
Photo from wikipedia

Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II

Sign Up to like & get
recommendations! Published in 2017 at "Cell Reports"

DOI: 10.1016/j.celrep.2017.02.018

Abstract: Summary Acetyl coenzyme A (AcCoA), a key intermediate in mitochondrial metabolism, N-acetylates lysine residues, disrupting and, in some cases, regulating protein function. The mitochondrial lysine deacetylase Sirtuin 3 (Sirt3) reverses this modification with benefits reported… read more here.

Keywords: glyoxalase; acetylation; lysine; lysine acetylation ... See more keywords
Photo by stuchy from unsplash

Insights into citric acid-induced cadmium tolerance and phytoremediation in Brassica juncea L.: Coordinated functions of metal chelation, antioxidant defense and glyoxalase systems.

Sign Up to like & get
recommendations! Published in 2018 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2017.09.045

Abstract: Cadmium (Cd) is a serious environmental threat because it accumulates in plants from soil and is subsequently transported into the food cycle. Increased Cd uptake in plants disrupts plant metabolism and hampers crop growth and… read more here.

Keywords: glyoxalase; tolerance; content; defense glyoxalase ... See more keywords
Photo from wikipedia

The Human Glyoxalase Gene Family in Health and Disease.

Sign Up to like & get
recommendations! Published in 2022 at "Chemical research in toxicology"

DOI: 10.1021/acs.chemrestox.2c00182

Abstract: The glyoxalase gene family consists of six structurally and functionally diverse enzymes with broad roles in metabolism. The common feature that defines this family is based on structural motifs that coordinate divalent cations which are… read more here.

Keywords: family; disease; gene family; glyoxalase gene ... See more keywords
Photo by cdc from unsplash

Neural Glyoxalase Pathway Enhancement by Morin Derivatives in an Alzheimer's Disease Model.

Sign Up to like & get
recommendations! Published in 2020 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.9b00566

Abstract: The gyloxalase pathway (GP) is an antioxidant defense system that detoxifies metabolic byproduct methylglyoxal (MG). Through sequential reactions, reduced glutathione (GSH), glyoxalase I (glo-1), and glyoxalase II (glo-2) convert MG into D-lactate. Spontaneous reactions involving… read more here.

Keywords: glyoxalase; alzheimer disease; pathway; morin derivatives ... See more keywords
Photo from wikipedia

Al-induced proteomics changes in tomato plants over-expressing a glyoxalase I gene.

Sign Up to like & get
recommendations! Published in 2020 at "Horticulture research"

DOI: 10.1038/s41438-020-0264-x

Abstract: Glyoxalase I (Gly I) is the first enzyme in the glutathionine-dependent glyoxalase pathway for detoxification of methylglyoxal (MG) under stress conditions. Transgenic tomato 'Money Maker' plants overexpressing tomato SlGlyI gene (tomato unigene accession SGN-U582631/Solyc09g082120.3.1) were… read more here.

Keywords: glyoxalase; control; treated conditions; tomato plants ... See more keywords