Glypican-3 induces oncogenicity by preventing IGF-1R degradation, a process that can be blocked by Grb10
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19035
Abstract: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a major cause of cancer-related death worldwide. Previously, we demonstrated that glypican-3 (GPC3) is highly expressed in HCC, and that GPC3 induces oncogenicity… read more here.
Keywords: degradation; induces oncogenicity; glypican induces; gpc3 ... See more keywords