A sustainable strategy for the assembly of Glypromate® and its structurally-related analogues by tandem sequential peptide coupling
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DOI: 10.1039/d0gc00143k
Abstract: This work describes an improved and greener methodology of solution-phase synthesis for the preparation of Glypromate® (glycyl-L-prolyl-L-glutamic acid, GPE), a potent neuropeptide for applications in neurodegenerative conditions such as Huntington's, Parkinson's and Alzheimer's diseases. This… read more here.
Keywords: peptide; sequential peptide; structurally related; glypromate ... See more keywords