Gangliosides in the differentiation process of primary neurons: the specific role of GM1-oligosaccharide
Sign Up to like & getrecommendations! Published in 2020 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-020-09919-x
Abstract: It has been recently reported by our group that GM1-oligosaccharide added to neuroblastoma cells or administered to mouse experimental model mimics the neurotrophic and neuroprotective properties of GM1 ganglioside. In addition to this, differently from… read more here.
Keywords: gm1; role gm1; differentiation; gm1 oligosaccharide ... See more keywords
The Neuroprotective Role of the GM1 Oligosaccharide, II3Neu5Ac-Gg4, in Neuroblastoma Cells
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DOI: 10.1007/s12035-019-1556-8
Abstract: Recently, we demonstrated that the GM1 oligosaccharide, II3Neu5Ac-Gg4 (OligoGM1), administered to cultured murine Neuro2a neuroblastoma cells interacts with the NGF receptor TrkA, leading to the activation of the ERK1/2 downstream pathway and to cell differentiation.… read more here.
Keywords: ii3neu5ac gg4; gm1; gm1 oligosaccharide; oligosaccharide ii3neu5ac ... See more keywords