Loss of GM130 does not impair oocyte meiosis and embryo development in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.08.055
Abstract: Golgi matrix protein 130 (GM130), encoded by GOLGA2, is the classical marker of the Golgi apparatus. It plays important roles in various mitotic events, such as interacting with importin-alpha and liberating spindle assembly factor TPX2… read more here.
Keywords: loss gm130; gm130; mice; gm130 impair ... See more keywords
Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-α
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-12207-4
Abstract: To facilitate proper mitotic cell partitioning, the Golgi disassembles by suppressing vesicle fusion. However, the underlying mechanism has not been characterized previously. Here, we report a Ran pathway-independent attenuation mechanism that allows Importin-α (a nuclear… read more here.
Keywords: golgi disassembly; gm130; golgi; ran pathway ... See more keywords
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Nephrology"
DOI: 10.1159/000499110
Abstract: Background: Aberrant O-glycosylation IgA1 production is a major factor in the pathogenesis of IgA nephropathy, but the underlying mechanism is still unclear. IgA1 glycosylation modification is in Golgi, and downregulation of the Golgi peripheral membrane… read more here.
Keywords: iga nephropathy; gm130; iga1 glycosylation; glycosylation ... See more keywords