Articles with "gm3 neu5gc" as a keyword



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Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-46148-1

Abstract: The GM3(Neu5Gc) ganglioside represents a tumor-specific antigen that is considered a promising target for cancer immunotherapy. We previously demonstrated that the humanized antibody 14F7hT, specific for this ganglioside, exhibited significant antitumor effects in preclinical hematological… read more here.

Keywords: gm3 neu5gc; ganglioside; antibody; antitumor effects ... See more keywords