α-Lipoic acid blocks the GMCSF induced protease/protease inhibitor spectrum associated with fetal membrane weakening in-vitro.
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DOI: 10.1016/j.placenta.2020.06.021
Abstract: INTRODUCTION We use an in-vitro human fetal membrane (FM) explant-based model to study inflammation-induced FM weakening, a prerequisite for PPROM. In this system, GMCSF is a critical intermediate, both necessary and sufficient for TNFα and… read more here.
Keywords: protease inhibitor; gmcsf induced; protease; induced weakening ... See more keywords