International Forum on GMP‐grade human platelet lysate for cell propagation: summary
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DOI: 10.1111/vox.12593
Abstract: D. Strunk, M. Lozano, D. C. Marks, Y. S. Loh, G. Gstraunthaler, H. Schennach, E. Rohde, S. Laner-Plamberger, M. € Oller, J. Nystedt, R. Lotfi, M. Rojewski, H. Schrezenmeier, K. Bieback, R. Sch€afer, T. Bakchoul,… read more here.
Keywords: grade human; international forum; forum gmp; gmp grade ... See more keywords
Genomic, Metabolic, and Immunological Characterization of GMP-Grade Mycobacterium phlei
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DOI: 10.1128/spectrum.00070-22
Abstract: Heat-inactivated M. phlei demonstrates promising efficacy to treat BCG-unresponsive non-muscle-invasive bladder cancer patients in clinical trials. However, lack of GMP-grade heat-inactivated M. phlei hampers further clinical investigations. ABSTRACT Mycobacterium phlei (M. phlei) is an understudied… read more here.
Keywords: heat inactivated; mycobacterium phlei; gmp grade; inactivated phlei ... See more keywords
GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01062
Abstract: γ9δ2T cells play a critical role in daily cancer immune surveillance by sensing cancer-mediated metabolic changes. However, a major limitation of the therapeutic application of γ9δ2T cells is their diversity and regulation through innate co-receptors.… read more here.
Keywords: cells engineered; express defined; gmp grade; engineered express ... See more keywords
GMP-Grade Manufacturing and Quality Control of a Non-Virally Engineered Advanced Therapy Medicinal Product for Personalized Treatment of Age-Related Macular Degeneration
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DOI: 10.3390/biomedicines10112777
Abstract: The introduction of new therapeutics requires validation of Good Manufacturing Practice (GMP)-grade manufacturing including suitable quality controls. This is challenging for Advanced Therapy Medicinal Products (ATMP) with personalized batches. We have developed a person-alized, cell-based… read more here.
Keywords: advanced therapy; quality; grade manufacturing; gmp grade ... See more keywords