Minimal clonal plasma cell contamination of peripheral stem cell grafts have an adverse prognostic impact in patients with multiple myeloma undergoing autologous transplantation.
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DOI: 10.1159/000548496
Abstract: Introduction The significance of autografts' contamination by clonal plasma cells on clinical outcome in newly diagnosed multiple myeloma remains controversial. Methods We retrospectively reviewed the clinical and laboratory data of newly diagnosed multiple myeloma (NDMM)… read more here.
Keywords: multiple myeloma; stem cell; response; cell ... See more keywords
Predictive Value of Clonal Plasma Cells in Autografts Assessed By Next Generation Flow Cytometry on Pre-Transplant Bone Marrow MRD in Multiple Myeloma Patients
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DOI: 10.1182/blood-2024-204692
Abstract: Background: High-dose melphalan followed by autologous stem cell transplantation (ASCT) represents the standard of care for multiple myeloma (MM) patients. However, the clinical significance of minimal residual disease (MRD) in hematopoietic cell grafts (gMRD) remains… read more here.
Keywords: pre asct; gmrd; asct mrd; asct ... See more keywords