Gingival mesenchymal stem cells attenuate pro-inflammatory macrophages stimulated with oxidized low-density lipoprotein and modulate lipid metabolism.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2018.11.007
Abstract: OBJECTIVE To examine the effects of gingival mesenchymal stem cells (GMSCs) on inflammatory macrophages upon oxidized low-density lipoprotein (ox-LDL) stimulation and evaluate therapeutic potential of GMSCs on mouse model of periodontitis associated with hyperlipidemia. METHODS… read more here.
Keywords: oxidized low; density lipoprotein; gmscs; density ... See more keywords
Role of gingival mesenchymal stem cell exosomes in macrophage polarization under inflammatory conditions.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.106030
Abstract: OBJECTIVE Exosomes have been shown to play a strong role in intercellular communication. While GMSCs have been extensively studied, less research exists on exosomes derived from GMSCs, especially on how exosomes affect macrophages. This study… read more here.
Keywords: macrophage polarization; gmscs; inflammatory conditions; role ... See more keywords
Anti-apoptotic effects of human gingival mesenchymal stromal cells on polymorphonuclear leukocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Oral diseases"
DOI: 10.1111/odi.13768
Abstract: OBJECTIVES Polymorphonuclear leukocytes (PMNs) constitute the first line of host defence and are crucial in maintaining periodontal health. Their survival and function are modulated by mesenchymal stromal cells (MSCs) from different origin. Gingival MSCs (GMSCs)… read more here.
Keywords: mesenchymal stromal; polymorphonuclear leukocytes; anti apoptotic; apoptotic effects ... See more keywords
The Role of Hypoxia on the Neuronal Differentiation of Gingival Mesenchymal Stem Cells: A Transcriptional Study
Sign Up to like & getrecommendations! Published in 2019 at "Cell Transplantation"
DOI: 10.1177/0963689718814470
Abstract: Mesenchymal stem cells (MSCs) are widely used in stem cell therapy for regenerative purposes. Oral-derived MSCs, such as gingival MSCs (GMSCs), deriving from the neural crest seem more suitable to differentiate toward the neuronal lineage.… read more here.
Keywords: stem; hypoxia preconditioning; neuronal differentiation; gmscs ... See more keywords