Self-assembled micelles based on gambogenic acid-phospholipid complex for sustained-release drug delivery
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2019.1656294
Abstract: Abstract Objective: To improve the water solubility and enhance the oral bioavailability of gambogenic acid (GNA). Methods: GNA-phospholipid complex (GNA-PLC) micelles were successfully prepared by anti-solvent method. Results: The encapsulation efficiency of GNA-PLC micelles can… read more here.
Keywords: gna plc; gna; plc micelles; sustained release ... See more keywords
A-80 Global Neuropsychological Assessment (GNA): Preliminary Evidence of Clinical Utility
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Clinical Neuropsychology"
DOI: 10.1093/arclin/acz034.80
Abstract: The Global Neuropsychological Assessment (GNA) is an 18-minute cognitive test battery with seven subtests that is being translated into multiple languages and standardized worldwide. This study seeks to evaluate the GNA’s ability to discriminate patients… read more here.
Keywords: assessment gna; gna; healthy controls; neuropsychological assessment ... See more keywords
Preliminary Validation of the Global Neuropsychological Assessment in Alzheimer's Disease and Healthy Volunteers.
Sign Up to like & getrecommendations! Published in 2021 at "Assessment"
DOI: 10.1177/1073191121991221
Abstract: METHODS We administered the Global Neuropsychological Assessment (GNA), an abbreviated cognitive battery, to 105 adults aged 73.0 ± 7.1 years, including 28 with probable Alzheimer's disease, 9 with amnestic mild cognitive impairment, and 68 healthy… read more here.
Keywords: gna; alzheimer disease; neuropsychological assessment; global neuropsychological ... See more keywords
Acyclic (S)-glycol nucleic acid (S-GNA) modification of siRNAs improves the safety of RNAi therapeutics while maintaining potency
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DOI: 10.1261/rna.079526.122
Abstract: Glycol nucleic acid (GNA) is an acyclic nucleic acid analog connected via phosphodiester bonds. Crystal structures of RNA–GNA chimeric duplexes indicated that nucleotides of the right-handed (S)-GNA were better accommodated in the right-handed RNA duplex… read more here.
Keywords: acid gna; glycol nucleic; gna; nucleic acid ... See more keywords
Gambogenic acid inhibits the proliferation of small-cell lung cancer cells by arresting the cell cycle and inducing apoptosis
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DOI: 10.3892/or.2018.6950
Abstract: Gambogenic acid (GNA), which is an important active compound present in gamboge, exerts anticancer activity in various types of tumor cells. However, the effect of GNA on small-cell lung cancer (SCLC) cell lines and the… read more here.
Keywords: apoptosis; gna; cell cycle; gambogenic acid ... See more keywords