GNAT toxins evolve toward narrow tRNA target specificities
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac356
Abstract: Abstract Type II toxin–antitoxin (TA) systems are two-gene modules widely distributed among prokaryotes. GNAT toxins associated with the DUF1778 antitoxins represent a large family of type II TAs. GNAT toxins inhibit cell growth by disrupting… read more here.
Keywords: evolve toward; gnat; narrow trna; toxins evolve ... See more keywords
Comparative Analysis of Diverse Acetyltransferase-Type Toxin-Antitoxin Loci in Klebsiella pneumoniae
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00320-22
Abstract: Elucidating the roles of multifaceted GNAT-RHH TA loci is essential for understanding how these TAs interact among themselves. Recently, the reaction mechanisms and structures of several GNAT-RHH pairs have been reported. ABSTRACT Toxin-antitoxin (TA) modules… read more here.
Keywords: gnat; gnat rhh; pneumoniae; toxin ... See more keywords