Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2024638
Abstract: ABSTRACT Shikonin (SHK), a major component of shiverweed, was provided with anti-tumor effects via multiple targets and signal pathways. Nevertheless, the specific mechanism of its function in colorectal cancer (CRC) still needed to be further… read more here.
Keywords: 545 guanine; gnb1; mir 545; crc ... See more keywords
AFAP1 antisense RNA 1 promotes retinoblastoma progression by sponging microRNA miR-545-3p that targets G protein subunit beta 1
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2033464
Abstract: ABSTRACT The oncogenic role of actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) has been reported in retinoblastoma (RB). However, the underlying regulatory mechanisms remain poorly understood. In this study, reverse transcription-quantitative polymerase chain reaction… read more here.
Keywords: gnb1; afap1 as1; mir 545; migration ... See more keywords
GNB1 promotes hepatocellular carcinoma progression by targeting BAG2 to activate P38/MAPK signaling
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Science"
DOI: 10.1111/cas.15741
Abstract: G‐proteins are intracellular partners of G‐protein‐coupled receptors. As a member of the G‐protein family, GNB1 has been shown to play a pro‐cancer role in lung cancer and breast cancer. However, the biological function and detailed… read more here.
Keywords: hepatocellular carcinoma; carcinoma progression; gnb1; hcc ... See more keywords