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Published in 2021 at "Chemmedchem"
DOI: 10.1002/cmdc.202100113
Abstract: PROteolysis TArgeting Chimeras (PROTACs) promote the degradation, rather than inhibition, of a drug target as a mechanism for therapeutic treatment. Bifunctional PROTAC molecules allow simultaneous binding of both the target protein and an E3‐Ubiquitin ligase,…
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Keywords:
gne 987;
native mass;
ternary complexes;
mass spectrometry ... See more keywords