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Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29836
Abstract: To determine the mechanism by which D‐site‐binding protein (Dbp) regulates rat calvarial osteoprogenitors (OPCs) osteogenic differentiation. α‐Smooth muscle actin (α‐SMA) + rat calvarial OPCs were extracted and purified using immunomagnetic beads. Cells were transduced with Dbp‐lentivirus and…
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Keywords:
kiss1 gnrh;
dbp;
differentiation;
gnrh ... See more keywords
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Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27443
Abstract: Gonadotropin‐releasing hormone (GnRH) is secreted from hypothalamic GnRH neurons and stimulates a GnRH receptor in gonadotroph cells and GnRH neurons. The GnRH receptor belongs to the G‐protein‐coupled receptors, and stimulation of the GnRH receptor activates…
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Keywords:
kinase;
pyk2;
cam kinase;
activation ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8618-7_19
Abstract: Gonadotropin-releasing hormone (GnRH) acts via G-protein coupled receptors on pituitary gonadotropes. These are Gq-coupled receptors that mediate acute effects of GnRH on the exocytotic secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well…
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Keywords:
hormone;
releasing hormone;
gonadotropin releasing;
gnrh signaling ... See more keywords
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Published in 2018 at "Forensische Psychiatrie, Psychologie, Kriminologie"
DOI: 10.1007/s11757-018-0503-2
Abstract: ZusammenfassungAktuelle Leitlinien empfehlen den Einsatz einer antiandrogenen Medikation parallel zu psychotherapeutischen Verfahren in der Behandlung von Patienten und Sexualstraftätern mit einer schweren paraphilen Symptomatik und einem hohen bis sehr hohen Risiko für die Begehung schwerer…
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Keywords:
behandlung;
mit gnrh;
der;
gnrh agonisten ... See more keywords
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Published in 2017 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-017-0627-9
Abstract: Puberty is a major developmental stage. Damaging mutations, considered as “mistakes of nature”, have contributed to the unraveling of the networks implicated in the normal initiation of puberty. Genes involved in the abnormal hypothalamic–pituitary–gonadal (HPG)…
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Keywords:
precocious puberty;
genetics;
puberty initiation;
gnrh ... See more keywords
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Published in 2020 at "Agri Gene"
DOI: 10.1016/j.aggene.2019.100099
Abstract: Abstract Gonadotropin-releasing hormone (GnRH) is a key neuropeptide of vertebrates, involved in gonadal maturation and primarily regulated by the hypothalamic-pituitary-gonadal axis. The full length GnRH-like cDNA isolated from the cerebral ganglion of Haliotis discus hannai,…
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Keywords:
gnrh like;
gnrh;
discus hannai;
expression ... See more keywords
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Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2020.735911
Abstract: Abstract Gonadotropin-releasing hormone (GnRH) is a key hypothalamic neuropeptide regulating the reproductive function of vertebrates and invertebrates. In the present study, we report the role of GnRH in gamete cell proliferation of Pacific abalone, Haliotis…
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Keywords:
abalone;
discus hannai;
proliferation;
gnrh ... See more keywords
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Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.12.095
Abstract: We investigated a series of uracil analogues by introducing various substituents on the phenyl ring of the N-3 aminoethyl side chain and evaluated their antagonistic activity against human gonadotropin-releasing hormone (GnRH) receptors. Analogues with substituents…
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Keywords:
releasing hormone;
gonadotropin releasing;
hormone gnrh;
gnrh ... See more keywords
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Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.01.041
Abstract: Peptide-drug conjugates have emerged as a potent approach to enhance the targeting and pharmacokinetic profiles of drugs. However, the impact of the linker unit has not been explored/exploited in depth. Gemcitabine (dFdC) is an anticancer…
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Keywords:
gemcitabine;
chemistry;
drug;
drug release ... See more keywords
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Published in 2019 at "Journal of Equine Veterinary Science"
DOI: 10.1016/j.jevs.2019.01.013
Abstract: ABSTRACT We tested the hypotheses that in winter anovulatory mares (1) both chronic daily injections of estradiol‐17&bgr; (E2) and subcutaneous E2 implants could enhance pituitary secretion of gonadotropins in response to continuous subcutaneous infusion of…
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Keywords:
hormone;
response;
infusion;
response continuous ... See more keywords
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Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2016.10.031
Abstract: We examined the role of PKCs and Ca2+ in GnRH-stimulated p38MAPK phosphorylation in the gonadotrope derived αT3-1 and LβT2 cell lines. GnRH induced a slow and rapid increase in p38MAPK phosphorylation in αT3-1 and LβT2…
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Keywords:
gonadotrope;
pkcs ca2;
p38mapk phosphorylation;
gnrh ... See more keywords