Illuminating the terminal nerve: Uncovering the link between GnRH‐1 neuron and olfactory development
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25599
Abstract: During embryonic development, the olfactory placode (OP) generates migratory neurons, including olfactory pioneer neurons, cells of the terminal nerve (TN), gonadotropin‐releasing hormone‐1 (GnRH‐1) neurons, and other uncharacterized neurons. Pioneer neurons from the OP induce olfactory… read more here.
Keywords: terminal nerve; olfactory; gnrh neuron; gnrh ... See more keywords
Unraveling Hypothalamus‐Pituitary dysregulation: Hypergonadotropism in F1 progeny due to prenatal exposure to hexavalent chromium
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23699
Abstract: The endocrine disruptor hexavalent chromium [Cr(VI)] is a proven reproductive toxicant. We recently demonstrated that prenatal Cr(VI) exposure causes testicular resistance to gonadotropins, resulting in hypergonadotropic hypoandrogenism in F1 rats. However, the mechanism driving hypergonadotropism… read more here.
Keywords: receptor; hexavalent chromium; hypergonadotropism; gnrh ... See more keywords
Circadian transcription factor Dbp promotes rat calvarial osteoprogenitors osteogenic differentiation through Kiss1/GnRH/E2 signaling pathway loop
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29836
Abstract: To determine the mechanism by which D‐site‐binding protein (Dbp) regulates rat calvarial osteoprogenitors (OPCs) osteogenic differentiation. α‐Smooth muscle actin (α‐SMA) + rat calvarial OPCs were extracted and purified using immunomagnetic beads. Cells were transduced with Dbp‐lentivirus and… read more here.
Keywords: kiss1 gnrh; dbp; differentiation; gnrh ... See more keywords
Activation of Pyk2 by CaM kinase II in cultured hypothalamic neurons and gonadotroph cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27443
Abstract: Gonadotropin‐releasing hormone (GnRH) is secreted from hypothalamic GnRH neurons and stimulates a GnRH receptor in gonadotroph cells and GnRH neurons. The GnRH receptor belongs to the G‐protein‐coupled receptors, and stimulation of the GnRH receptor activates… read more here.
Keywords: kinase; pyk2; cam kinase; activation ... See more keywords
Exploring Dynamics and Noise in Gonadotropin-Releasing Hormone (GnRH) Signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8618-7_19
Abstract: Gonadotropin-releasing hormone (GnRH) acts via G-protein coupled receptors on pituitary gonadotropes. These are Gq-coupled receptors that mediate acute effects of GnRH on the exocytotic secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well… read more here.
Keywords: hormone; releasing hormone; gonadotropin releasing; gnrh signaling ... See more keywords
The comparision among euploidy of preimplantation blastocysts in different controlled ovary stimulation (COH) protocols
Sign Up to like & getrecommendations! Published in 2024 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-024-07474-6
Abstract: To compare differences in euploidy rates for blastocysts in preimplantation genetic testing for aneuploidy (PGT-A) cycles after gonadotropin-releasing hormone agonist (GnRH-a) long and short protocols, GnRH-antagonist (GnRH-ant) protocol, progestin-primed ovarian stimulation and mild stimulation protocols,… read more here.
Keywords: rate; euploidy rate; gnrh; stimulation ... See more keywords
Die Behandlung paraphiler Störungen mit GnRH-Agonisten unter besonderer Berücksichtigung ethischer und rechtlicher Aspekte
Sign Up to like & getrecommendations! Published in 2018 at "Forensische Psychiatrie, Psychologie, Kriminologie"
DOI: 10.1007/s11757-018-0503-2
Abstract: ZusammenfassungAktuelle Leitlinien empfehlen den Einsatz einer antiandrogenen Medikation parallel zu psychotherapeutischen Verfahren in der Behandlung von Patienten und Sexualstraftätern mit einer schweren paraphilen Symptomatik und einem hohen bis sehr hohen Risiko für die Begehung schwerer… read more here.
Keywords: behandlung; mit gnrh; der; gnrh agonisten ... See more keywords
The mystery of puberty initiation: genetics and epigenetics of idiopathic central precocious puberty (ICPP)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-017-0627-9
Abstract: Puberty is a major developmental stage. Damaging mutations, considered as “mistakes of nature”, have contributed to the unraveling of the networks implicated in the normal initiation of puberty. Genes involved in the abnormal hypothalamic–pituitary–gonadal (HPG)… read more here.
Keywords: precocious puberty; genetics; puberty initiation; gnrh ... See more keywords
Characterization and expression analysis of a GnRH-like peptide in the Pacific abalone, Haliotis discus hannai
Sign Up to like & getrecommendations! Published in 2020 at "Agri Gene"
DOI: 10.1016/j.aggene.2019.100099
Abstract: Abstract Gonadotropin-releasing hormone (GnRH) is a key neuropeptide of vertebrates, involved in gonadal maturation and primarily regulated by the hypothalamic-pituitary-gonadal axis. The full length GnRH-like cDNA isolated from the cerebral ganglion of Haliotis discus hannai,… read more here.
Keywords: gnrh like; gnrh; discus hannai; expression ... See more keywords
In vivo effects of GnRH peptide on gonadal proliferation and related gene expression of Pacific abalone, Haliotis discus hannai
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2020.735911
Abstract: Abstract Gonadotropin-releasing hormone (GnRH) is a key hypothalamic neuropeptide regulating the reproductive function of vertebrates and invertebrates. In the present study, we report the role of GnRH in gamete cell proliferation of Pacific abalone, Haliotis… read more here.
Keywords: abalone; discus hannai; proliferation; gnrh ... See more keywords
Synthesis and biological evaluation of 3-(2-aminoethyl) uracil derivatives as gonadotropin-releasing hormone (GnRH) receptor antagonists.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.12.095
Abstract: We investigated a series of uracil analogues by introducing various substituents on the phenyl ring of the N-3 aminoethyl side chain and evaluated their antagonistic activity against human gonadotropin-releasing hormone (GnRH) receptors. Analogues with substituents… read more here.
Keywords: releasing hormone; gonadotropin releasing; hormone gnrh; gnrh ... See more keywords