Activation of PI3K/Akt prevents hypoxia/reoxygenation-induced GnRH decline via FOXO3a.
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DOI: 10.33549/physiolres.934861
Abstract: Recent studies have suggested that the hypothalamus has an important role in aging by regulating nuclear factor-?B (NF-?B)-directed gonadotropin-releasing hormone (GnRH) decline. Moreover, our previous study has shown that ischemia-reperfusion (IR) injury activates NF-?B to… read more here.
Keywords: decline; pi3k akt; activation pi3k; hypoxia reoxygenation ... See more keywords