In vivo imaging of the GnRH pulse generator reveals a temporal order of neuronal activation and synchronization during each pulse
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2117767119
Abstract: Significance Hypothalamic oscillators that generate pulsatile patterns of hormone secretion represent a fundamental physiological feature regulating homeostatic systems. How individual cells within these neural ensembles generate and coordinate episodic activity and resultant pulse secretion is… read more here.
Keywords: gnrh; gnrh pulse; generator; temporal order ... See more keywords
KNDy neurones and GnRH/LH pulse generation: Current understanding and future aspects.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neuroendocrinology"
DOI: 10.1111/jne.13285
Abstract: Uncovering the central mechanism underlying mammalian reproduction is warranted to develop new therapeutic approaches for reproductive disorders in humans and domestic animals. The present study focused on the role of arcuate kisspeptin neurones (also known… read more here.
Keywords: generation current; current understanding; kndy neurones; gnrh pulse ... See more keywords
Regulation of GnRH pulsatility in ewes.
Sign Up to like & getrecommendations! Published in 2018 at "Reproduction"
DOI: 10.1530/rep-18-0127
Abstract: Early work in ewes provided a wealth of information on the physiological regulation of pulsatile gonadotropin-releasing hormone (GnRH) secretion by internal and external inputs. Identification of the neural systems involved, however, was limited by the… read more here.
Keywords: gnrh; kndy neurons; gnrh pulse; kisspeptin ... See more keywords