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Published in 2018 at "Hormone Research in Paediatrics"
DOI: 10.1159/000493134
Abstract: Background: Recently, mutations of makorin RING finger protein 3 (MKRN3) have been identified in familial central precocious puberty (CPP). Serum levels of this protein decline before the pubertal onset in healthy girls and boys and…
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Keywords:
mkrn3;
gnrha treatment;
mkrn3 levels;
treatment ... See more keywords
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Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-mon-241
Abstract: Abstract Objectives: Small for gestational age (SGA) children may present an earlier onset of pubertal development, advanced bone maturation and reduced final height. The aim of this study was to compare the clinical parameters such…
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Keywords:
gnrha treatment;
treatment;
sga;
height ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0185080
Abstract: The adult height of children with early onset puberty is limited by the premature maturation of hypothalamic-pituitary-gonadal axis. To evaluate the effects of gonadotropin-releasing hormone analog (GnRHa) treatment on the final height (FH) and bone…
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Keywords:
gnrha treatment;
study;
icpp;
puberty ... See more keywords
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Published in 2021 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2020-0471
Abstract: Abstract Background The impact of gonadotropin-releasing-hormone-analogue (GnRHa) treatment on weight and body composition is controversial. Exploring the nutritional, psychological patterns of this population may aid to clarify this propensity to gain weight. This prospective observational…
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Keywords:
gnrha treatment;
body composition;
cpp efp;
quality life ... See more keywords