Adolescent chronic unpredictable stress causes a bias in goal-directed behavior and distinctively changes the expression of NMDA and dopamine receptors in the dorsomedial and dorsolateral striatum in male rats.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental psychobiology"
DOI: 10.1002/dev.22235
Abstract: The distinct preferences between goal-directed and habit-directed behaviors involve numerous neurodegenerative and psychiatric disorders. Chronic stress during adulthood biases behavior toward habit-oriented strategies. However, it remains to be studied how adolescence, as a stage in… read more here.
Keywords: stress; goal directed; striatum; chronic unpredictable ... See more keywords
A model for transforming egocentric views into goal‐directed behavior
Sign Up to like & getrecommendations! Published in 2023 at "Hippocampus"
DOI: 10.1002/hipo.23510
Abstract: Neurons in the rat postrhinal cortex (POR) respond to the egocentric (observer‐centered) bearing and distance of the boundaries, or geometric center, of an enclosed space. Understanding of the precise geometric and sensory properties of the… read more here.
Keywords: transforming egocentric; goal directed; egocentric views; model ... See more keywords
Influence of the initial level of consciousness on early, goal-directed mobilization: a post hoc analysis
Sign Up to like & getrecommendations! Published in 2019 at "Intensive Care Medicine"
DOI: 10.1007/s00134-019-05528-x
Abstract: PurposeEarly mobilization within 72 h of intensive care unit (ICU) admission improves functional status at hospital discharge. We aimed to assess the effectiveness of early, goal-directed mobilization in critically ill patients across a broad spectrum of… read more here.
Keywords: early goal; goal directed; mobilization; post ... See more keywords
When socially excluded people prefer moralizing to anti- and prosocial behavior: Support for a goal-directed account
Sign Up to like & getrecommendations! Published in 2020 at "Motivation and Emotion"
DOI: 10.1007/s11031-020-09826-6
Abstract: According to the temporal need-threat model, different responses toward social exclusion stem from the fact that different needs are threatened. Because evidence for this account is mixed, we tested a goal-directed account in which the… read more here.
Keywords: account; prosocial behavior; directed account; goal directed ... See more keywords
Stress-induced reliance on habitual behavior is moderated by cortisol reactivity
Sign Up to like & getrecommendations! Published in 2019 at "Brain and Cognition"
DOI: 10.1016/j.bandc.2018.05.005
Abstract: Instrumental learning, i.e., learning that specific behaviors lead to desired outcomes, occurs through goal-directed and habit memory systems. Exposure to acute stress has been shown to result in less goal-directed control, thus rendering behavior more… read more here.
Keywords: stress induced; cortisol reactivity; stress; goal directed ... See more keywords
Decoding route selection of pigeon during goal-directed behavior: A joint spike-LFP study
Sign Up to like & getrecommendations! Published in 2021 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2021.113289
Abstract: How to reach the goal is one of the core problems that animals must solve to complete goal-directed behavior. Studies have proved the important role of hippocampus (Hp) in spatial navigation and shown that Hp… read more here.
Keywords: goal; directed behavior; spike; goal directed ... See more keywords
Connections of the Mouse Orbitofrontal Cortex and Regulation of Goal-Directed Action Selection by Brain-Derived Neurotrophic Factor
Sign Up to like & getrecommendations! Published in 2017 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2015.10.026
Abstract: BACKGROUND Distinguishing between actions that are more likely or less likely to be rewarded is a critical aspect of goal-directed decision making. However, neuroanatomic and molecular mechanisms are not fully understood. METHODS We used anterograde… read more here.
Keywords: goal; selection; goal directed; factor ... See more keywords
Costly habitual avoidance is reduced by concurrent goal-directed approach in a modified devaluation paradigm.
Sign Up to like & getrecommendations! Published in 2021 at "Behaviour research and therapy"
DOI: 10.1016/j.brat.2021.103964
Abstract: Avoidance habits potentially contribute to maintaining maladaptive, costly avoidance behaviors that persist in the absence of threat. However, experimental evidence about costly habitual avoidance is scarce. In two experiments, we tested whether extensively trained avoidance… read more here.
Keywords: goal directed; habitual avoidance; directed approach; avoidance ... See more keywords
The goal-directed model as an alternative to reductionist and network approaches of psychopathology.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in psychology"
DOI: 10.1016/j.copsyc.2021.03.014
Abstract: As an alternative to biological reductionist and network approaches to psychopathology, we propose a nonreductionist mental-mechanistic approach. To illustrate this approach, we work out the implications of the goal-directed framework of Moors et al., which has… read more here.
Keywords: reductionist network; approaches psychopathology; network approaches; goal directed ... See more keywords
Goal directed enoxaparin dosing provides superior chemoprophylaxis against deep vein thrombosis.
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DOI: 10.1016/j.injury.2016.10.039
Abstract: INTRODUCTION Optimal enoxaparin dosing for deep venous thrombosis (DVT) prophylaxis remains elusive. Prior research demonstrated that trauma patients at increased risk for DVT based upon Greenfield's risk assessment profile (RAP) have DVT rates of 10.8%… read more here.
Keywords: goal; enoxaparin dosing; anti levels; goal directed ... See more keywords
American Society of Biomechanics Journal of Biomechanics Award 2018: Adaptive motor planning of center-of-mass trajectory during goal-directed walking in novel environments.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biomechanics"
DOI: 10.1016/j.jbiomech.2019.07.030
Abstract: To aid in the successful execution of goal-directed walking (discrete movement from a start location to an end target) the central nervous system forms a predictive motor plan. For the motor plan to be effective,… read more here.
Keywords: trajectory; biomechanics; directed walking; motor ... See more keywords