Immunoresolvent Resolvin D1 Maintains the Health of the Ocular Surface.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-21735-8_3
Abstract: The present review focuses on the role of one of the D-series resolvins (Rv) RvD1 in the regulation of conjunctival goblet cell secretion and its role in ocular surface health. RvD1 is the most thoroughly… read more here.
Keywords: secretion; ocular surface; mucin; surface ... See more keywords
CDX-2 Expression in Esophageal Biopsies Without Goblet Cell Intestinal Metaplasia May Be Predictive of Barrett’s Esophagus
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05914-x
Abstract: Background CDX-2 is a nuclear homeobox transcription factor not normally expressed in esophageal and gastric epithelia, reported to highlight intestinal metaplasia (IM) in the esophagus. Pathological absence of goblet cells at initial screening via hematoxylin… read more here.
Keywords: intestinal metaplasia; barrett esophagus; goblet; cdx ... See more keywords
Inflammation, vascularization and goblet cell differences in LSCD: Validating animal models of corneal alkali burns.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.05.005
Abstract: Limbal stem cell deficiency (LSCD) is one of the serious cause of visual impairment and blindness with loss of corneal clarity and vascularization. Factors such as ocular burns (acids, lime, thermal), genetic disorders or infections… read more here.
Keywords: models lscd; vascularization; goblet; inflammation ... See more keywords
Nod-Like Receptor Pyrin-Containing Protein 6 (NLRP6) Is Up-regulated in Ileal Crohn’s Disease and Differentially Expressed in Goblet Cells
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2018.03.001
Abstract: A contributing factor in the development of ulcerative colitis (UC) and Crohn’s disease (CD) is aberrant signaling of the innate immune complex known as the inflammasome. The inflammasome regulates the production of interleukin (IL)1b and… read more here.
Keywords: protein; goblet; disease; nod like ... See more keywords
Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2021.01.017
Abstract: Background & Aims Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell dysfunction have been attributed to the pathology of ulcerative colitis (UC).… read more here.
Keywords: cell differentiation; energy; goblet; goblet cell ... See more keywords
Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical science"
DOI: 10.1042/cs20210778
Abstract: Ulcerative colitis (UC) is majorly associated with dysregulation of the dynamic cross-talk among microbial metabolites, intestinal epithelial cells, and macrophages. Several studies have reported the significant role of butyrate in host-microbiota communication. However, whether butyrate… read more here.
Keywords: macrophage; goblet; butyrate; goblet cell ... See more keywords
LOSS OF INTESTINAL EPITHELIAL PTPN2 SELECTIVELY IMPAIRS GOBLET CELL DIFFERENTIATION DURING TYPE I IMMUNITY RESPONSE
Sign Up to like & getrecommendations! Published in 2025 at "Gastroenterology"
DOI: 10.1053/j.gastro.2025.01.183
Abstract: Loss-of-function variants in the Protein Tyrosine Phosphatase non-receptor Type 2 (PTPN2) gene are associated with increased risk of Inflammatory Bowel Disease (IBD). PTPN2 encodes a tyrosine phosphatase that negatively regulates signaling pathways - including JAK-STAT… read more here.
Keywords: differentiation; mice; ptpn2; cell ... See more keywords
Goblet cells dictate viral tropism and pathogenesis in nasal and intestinal mucosae
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2514150122
Abstract: Significance We identify goblet cells as regulators of viral infections at mucosal surfaces. Goblet cell-derived mucus effectively shields nasal and intestinal epithelia from swine influenza virus (SIV) and porcine epidemic diarrhea virus (PEDV), with virus-driven… read more here.
Keywords: dictate viral; goblet; cells dictate; pathogenesis ... See more keywords
Cytokine and goblet cell gene expression in equine cyathostomin infection and larvicidal anthelmintic therapy
Sign Up to like & getrecommendations! Published in 2020 at "Parasite Immunology"
DOI: 10.1111/pim.12709
Abstract: The role of the immune response to cyathostomin infections in horses remains unknown. Intestinal goblet cell hyperplasia has previously been noted as a component in cyathostomin infection; however, the function is unclear. The goal of… read more here.
Keywords: cyathostomin infection; goblet; gene expression; cyathostomin ... See more keywords
Proportion of goblet cell is associated with malignant potential in invasive mucinous adenocarcinoma of the lung
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DOI: 10.1111/pin.12853
Abstract: Invasive mucinous adenocarcinoma (IMA) is a newly classified variant of lung adenocarcinoma. The aim of this study was to examine the correlation between the proportion of goblet cells and the clinicopathological characteristics of IMA. Ninety‐nine… read more here.
Keywords: proportion goblet; cell proportion; goblet; goblet cell ... See more keywords
Clearance of small intestinal crypts involves goblet cell mucus secretion by intracellular granule rupture and enterocyte ion transport
Sign Up to like & getrecommendations! Published in 2022 at "Science Signaling"
DOI: 10.1126/scisignal.abl5848
Abstract: Goblet cells in the small intestinal crypts contain large numbers of mucin granules that are rapidly discharged to clean bacteria from the crypt. Because acetylcholine released by neuronal and nonneuronal cells controls many aspects of… read more here.
Keywords: mucus secretion; goblet; crypt; goblet cells ... See more keywords